Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts
Genetic deficiency of alpha-L-iduronidase causes mucopolysaccharidosis type I (MPS-I)
disease, due to accumulation of glycosaminoglycans (GAGs) including …
disease, due to accumulation of glycosaminoglycans (GAGs) including …
Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts
Abstract Mucopolysaccharidosis type I (MPS-I) is a rare lysosomal storage disorder caused
by deficiency of the enzyme alpha-L-iduronidase, which removes iduronic acid in both …
by deficiency of the enzyme alpha-L-iduronidase, which removes iduronic acid in both …
[HTML][HTML] Computational modeling of the molecular basis for the calcium-dependence of the mannuronan C-5 epimerase AvAlgE6 from Azotobacter vinelandii
The mannuronan C-5 epimerases catalyze epimerization of β-d-mannuronic acid to α-l-
guluronic acid in alginate polymers. The seven extracellular Azotobacter vinelandii …
guluronic acid in alginate polymers. The seven extracellular Azotobacter vinelandii …
Cheetah-MS: a web server to model protein complexes using tandem cross-linking mass spectrometry data
Protein–protein interactions (PPIs) are central in many biological processes but difficult to
characterize, especially in complex, unfractionated samples. Chemical cross-linking …
characterize, especially in complex, unfractionated samples. Chemical cross-linking …
[HTML][HTML] Molecular docking analysis of a dermatan sulfate tetra-saccharide to human alpha-L-iduronidase
Human alpha-L-iduronidase (IDUA) is a 653 amino acid protein involved in the sequential
degradation of glycos-amino-glycans (GAG), heparan sulfate (HS), and dermatan sulfate …
degradation of glycos-amino-glycans (GAG), heparan sulfate (HS), and dermatan sulfate …
Engineering the extracellular matrix to model diseases and orchestrate regeneration
Z Söderlund - 2023 - portal.research.lu.se
The extracellular matrix is not only a scaffold to which cells attach, but it is also a matrix that
communicates cell signals. Because of the interplay between cells and the extracellular …
communicates cell signals. Because of the interplay between cells and the extracellular …