Molecular basis of mechanotransduction in living cells
OP Hamill, B Martinac - Physiological reviews, 2001 - journals.physiology.org
The simplest cell-like structure, the lipid bilayer vesicle, can respond to mechanical
deformation by elastic membrane dilation/thinning and curvature changes. When a protein is …
deformation by elastic membrane dilation/thinning and curvature changes. When a protein is …
Synthesis of models for excitable membranes, synaptic transmission and neuromodulation using a common kinetic formalism
Markov kinetic models were used to synthesize a complete description of synaptic
transmission, including opening of voltage-dependent channels in the presynaptic terminal …
transmission, including opening of voltage-dependent channels in the presynaptic terminal …
[BOOK][B] The synaptic organization of the brain
GM Shepherd - 2003 - books.google.com
It is widely recognized that the neural basis of brain function can be fully understood only by
integrating many disciplines at many levels. Studies of synaptic organization are bringing …
integrating many disciplines at many levels. Studies of synaptic organization are bringing …
[BOOK][B] Physical biology of the cell
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics
for undergraduate or graduate students. It maps the huge and complex landscape of cell …
for undergraduate or graduate students. It maps the huge and complex landscape of cell …
Structure of a glycerol-conducting channel and the basis for its selectivity
Membrane channel proteins of the aquaporin family are highly selective for permeation of
specific small molecules, with absolute exclusion of ions and charged solutes and without …
specific small molecules, with absolute exclusion of ions and charged solutes and without …
Shaker potassium channel gating. III: Evaluation of kinetic models for activation.
WN Zagotta, T Hoshi, RW Aldrich - The Journal of general physiology, 1994 - rupress.org
Predictions of different classes of gating models involving identical conformational changes
in each of four subunits were compared to the gating behavior of Shaker potassium …
in each of four subunits were compared to the gating behavior of Shaker potassium …
[HTML][HTML] Chance and design—proton transfer in water, channels and bioenergetic proteins
CA Wraight - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2006 - Elsevier
Proton transfer and transport in water, gramicidin and some selected channels and
bioenergetic proteins are reviewed. An attempt is made to draw some conclusions about …
bioenergetic proteins are reviewed. An attempt is made to draw some conclusions about …
Theoretical and computational models of biological ion channels
1. Introduction 172. Dynamics of many-body systems 192.1 Effective dynamics of reduced
systems 212.2 The constraint of thermodynamic equilibrium 242.3 Mean-field theories 253 …
systems 212.2 The constraint of thermodynamic equilibrium 242.3 Mean-field theories 253 …
Voltage gating of ion channels
FJ Sigworth - Quarterly reviews of biophysics, 1994 - cambridge.org
Voltage-gated ion channels are membrane proteins that play a central role in the
propagation and transduction of cellular signals (Hille, 1992). Calcium ions entering cells …
propagation and transduction of cellular signals (Hille, 1992). Calcium ions entering cells …
Energetics of ion conduction through the gramicidin channel
The free energy governing K+ conduction through gramicidin A channels is characterized by
using over 0.1 μs of all-atom molecular dynamics simulations with explicit solvent and …
using over 0.1 μs of all-atom molecular dynamics simulations with explicit solvent and …