New insights into targeting membrane lipids for cancer therapy

G Preta - Frontiers in Cell and Developmental Biology, 2020‏ - frontiersin.org
Modulation of membrane lipid composition and organization is currently develo** as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …

Recent progress in Zein nanoparticles: a promising approach for advancing Cancer therapy

MS Khan, M Fatima, G Gupta, S Md… - Journal of Drug Delivery …, 2024‏ - Elsevier
A holistic approach is now necessary in cancer research to address the patients' discomfort
and alleviate the shortcomings in chemotherapy treatment. Despite the existence of several …

Repurposing drugs targeting metabolic diseases for cancer therapeutics

J Pillai, A Ray, M Maan, M Dutta - Drug Discovery Today, 2023‏ - Elsevier
Highlights•Discovery of new drugs against cancer is of utmost importance.•Drug repurposing
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …

Cerium oxide nanoparticles/polyacrylonitrile nanofibers as impervious barrier against viral infections

MH Emam, RS Elezaby, SA Swidan, SA Loutfy… - Pharmaceutics, 2023‏ - mdpi.com
Background: Using face masks is one of the protective measures to reduce the transmission
rate of coronavirus. Its massive spread necessitates develo** safe and effective antiviral …

The skin delivery of tofacitinib citrate using transethosomes and hybridized ethosomes/nanostructured lipid carriers for vitiligo therapy: Dermatopharmacokinetics and …

H Hesham, M Rady, RM Hathout, M Abdel-Halim… - International Journal of …, 2022‏ - Elsevier
Vitiligo is an autoimmune disease where its current treatment strategies are lengthy in
course and do not guarantee complete cure. Tofacitinib citrate (JAK inhibitor) is a potential …

[HTML][HTML] Enzymes in the cholesterol synthesis pathway: interactomics in the cancer context

P Ershov, L Kaluzhskiy, Y Mezentsev, E Yablokov… - Biomedicines, 2021‏ - mdpi.com
A global protein interactome ensures the maintenance of regulatory, signaling and structural
processes in cells, but at the same time, aberrations in the repertoire of protein–protein …

Nose-to-brain delivery of 18β-Glycyrrhetinic acid using optimized lipid nanocapsules: A novel alternative treatment for Alzheimer's disease

SR Gad, RI El-Gogary, MY George… - International Journal of …, 2023‏ - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and the most relevant form of
dementia affecting people worldwide. AD was reported to be associated with increased …

Effect of screening for type 2 diabetes on risk of cardiovascular disease and mortality: a controlled trial among 139,075 individuals diagnosed with diabetes in …

RK Simmons, SJ Griffin, T Lauritzen, A Sandbæk - Diabetologia, 2017‏ - Springer
Aims/hypothesis There is continuing debate about the net benefits of population screening
for type 2 diabetes. We compared the risk of cardiovascular disease (CVD) and mortality …

Synchronizing In Silico, In Vitro, and In Vivo Studies for the Successful Nose to Brain Delivery of an Anticancer Molecule

SA Abd-Algaleel, AA Metwally… - Molecular …, 2021‏ - ACS Publications
Sesamol is a sesame seed constituent with reported activity against many types of cancer. In
this work, two types of nanocarriers, solid lipid nanoparticles (SLNs) and polymeric …

Herceptin-conjugated liposomes co-loaded with doxorubicin and simvastatin in targeted prostate cancer therapy

N Li, X **e, Y Hu, H He, X Fu… - American journal of …, 2019‏ - pmc.ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of cancer-related deaths among men. The
anthracycline doxorubicin (DOX) is used for the treatment of this disease, but its …