Primary progressive aphasia and the evolving neurology of the language network

MM Mesulam, EJ Rogalski, C Wieneke… - Nature Reviews …, 2014 - nature.com
Primary progressive aphasia (PPA) is caused by selective neurodegeneration of the
language-dominant cerebral hemisphere; a language deficit initially arises as the only …

Primary progressive aphasia

MM Mesulam - Annals of neurology, 2001 - Wiley Online Library
Primary progressive aphasia (PPA) is a focal dementia characterized by an isolated and
gradual dissolution of language function. The disease starts with word‐finding disturbances …

Linguistic features identify Alzheimer's disease in narrative speech

KC Fraser, JA Meltzer… - Journal of Alzheimer's …, 2015 - journals.sagepub.com
Background: Although memory impairment is the main symptom of Alzheimer's disease
(AD), language impairment can be an important marker. Relatively few studies of language …

A novel frontal pathway underlies verbal fluency in primary progressive aphasia

M Catani, MM Mesulam, E Jakobsen, F Malik… - Brain, 2013 - academic.oup.com
The frontal aslant tract is a direct pathway connecting Broca's region with the anterior
cingulate and pre-supplementary motor area. This tract is left lateralized in right-handed …

[KNIHA][B] Cognitive neuroscience of language

D Kemmerer - 2022 - taylorfrancis.com
Cognitive Neuroscience of Language provides an up-to-date, wide-ranging, and
pedagogically practical survey of the most important developments in this exciting field. It …

Connected speech production in three variants of primary progressive aphasia

SM Wilson, ML Henry, M Besbris, JM Ogar… - Brain, 2010 - academic.oup.com
Primary progressive aphasia is a clinical syndrome defined by progressive deficits isolated
to speech and/or language, and can be classified into non-fluent, semantic and logopenic …

Quantitative classification of primary progressive aphasia at early and mild impairment stages

MM Mesulam, C Wieneke, C Thompson, E Rogalski… - Brain, 2012 - academic.oup.com
The characteristics of early and mild disease in primary progressive aphasia are poorly
understood. This report is based on 25 patients with aphasia quotients> 85%, 13 of whom …

Primary progressive aphasia—a language-based dementia

MM Mesulam - New England Journal of Medicine, 2003 - Mass Medical Soc
Primary progressive aphasia is an atypical dementia in which language abilities deteriorate
while memory is relatively preserved. For many years, the principal signs and symptoms …

Automated classification of primary progressive aphasia subtypes from narrative speech transcripts

KC Fraser, JA Meltzer, NL Graham, C Leonard, G Hirst… - cortex, 2014 - Elsevier
In the early stages of neurodegenerative disorders, individuals may exhibit a decline in
language abilities that is difficult to quantify with standardized tests. Careful analysis of …

[HTML][HTML] Syntactic processing depends on dorsal language tracts

SM Wilson, S Galantucci, MC Tartaglia, K Rising… - Neuron, 2011 - cell.com
Frontal and temporal language areas involved in syntactic processing are connected by
several dorsal and ventral tracts, but the functional roles of the different tracts are not well …