The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …

Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Apoptosis, a type of programmed cell death that plays a key role in both healthy and
pathological conditions, releases extracellular vesicles such as apoptotic bodies and …

From yeast to mammals, autophagy is an important mechanism for sustaining cellular
homeostasis through facilitating the degradation and recycling of aged and cytotoxic …

Autophagy, once viewed exclusively as a cytoplasmic auto-digestive process, has its less
intuitive but biologically distinct non-degradative roles. One manifestation of these functions …

Background Treatment options for women presenting with triple negative breast cancer
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …

Bone remodeling is a tightly controlled mechanism in which osteoblasts (OB), the cells
responsible for bone formation, osteoclasts (OC), the cells specialized for bone resorption …

Autophagy and apoptosis are two important catabolic processes contributing to the
maintenance of cellular and tissue homeostasis. Autophagy controls the turnover of protein …

Caspases are a family of cysteine proteases widely known as the principal mediators of the
apoptotic cell death response, but considerably less so as the contributors to the regulation …

Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies,
contribute to rejection in organ transplant recipients. However, mechanisms of immunization …