While the vast majority of research involving creatine supplementation has focused on
skeletal muscle, there is a small body of accumulating research that has focused on creatine …

Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

There is a robust and compelling body of evidence supporting the ergogenic and
therapeutic role of creatine supplementation in muscle. Beyond these well-described effects …

There is emerging interest regarding the potential beneficial effects of creatine
supplementation on indices of brain health and function. Creatine supplementation can …

Context From an energy perspective, the brain is very metabolically demanding. It is well
documented that creatine plays a key role in brain bioenergetics. There is some evidence …

Introduction Mental fatigue (MF) is a psychobiological state that impairs cognitive as well as
physical performance in different settings. Recently, numerous studies have sought ways to …

Mental load and fatigue are important causes of performance decreases and accidents in
different activities. However, a robust systematic review, detailing the instruments used to …

Background The negative effect of mental fatigue (MF) on physical performance has recently
been questioned. One reason behind this could lie in the interindividual differences in MF …

Introduction The discussion on the mechanism (s) underlying mental fatigue is still ongoing.
We want to reconfirm a performance-impairing effect of executing a lengthy cognitive task on …

New Findings What is the topic of this review? It provides an overview of the recent papers
linking brain neurotransmission with exercise‐induced and/or mental fatigue. What …