Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture

AA Ellero, I Van den Bout, M Vlok, AD Cromarty… - Scientific Reports, 2021 - nature.com
Three-dimensional models are considered a powerful tool for improving the concordance
between in vitro and in vivo phenotypes. However, the duration of spheroid culture may …

Characterisation of inducible proteins in the HepG2 cell line proteome

AA Ellero - 2022 - search.proquest.com
Rationale: Attaining scientifically robust, clinically representative, and functionally
translatable preclinical models for pharmaceutical research has become increasingly …