Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke
P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …
Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission
Executive summary Stroke is the second leading cause of death worldwide. The burden of
disability after a stroke is also large, and is increasing at a faster pace in low-income and …
disability after a stroke is also large, and is increasing at a faster pace in low-income and …
Endovascular thrombectomy with or without intravenous alteplase in acute stroke
P Yang, Y Zhang, L Zhang, Y Zhang… - … England Journal of …, 2020 - Mass Medical Soc
Background In acute ischemic stroke, there is uncertainty regarding the benefit and risk of
administering intravenous alteplase before endovascular thrombectomy. Methods We …
administering intravenous alteplase before endovascular thrombectomy. Methods We …
Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study
MHC Duvekot, E Venema, AD Rozeman… - The Lancet …, 2021 - thelancet.com
Background Due to the time-sensitive effect of endovascular treatment, rapid prehospital
identification of large-vessel occlusion in individuals with suspected stroke is essential to …
identification of large-vessel occlusion in individuals with suspected stroke is essential to …
Randomized assessment of rapid endovascular treatment of ischemic stroke
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …
to 80% of patients die within 90 days after stroke onset or do not regain functional …
Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial
Background Tenecteplase is a newer thrombolytic agent with some pharmacological
advantages over alteplase. Previous phase 2 trials of tenecteplase in acute ischaemic stroke …
advantages over alteplase. Previous phase 2 trials of tenecteplase in acute ischaemic stroke …
Indications for mechanical thrombectomy for acute ischemic stroke: current guidelines and beyond
Purpose of the Review This article reviews recent breakthroughs in the treatment of acute
ischemic stroke, mainly focusing on the evolution of endovascular thrombectomy, its impact …
ischemic stroke, mainly focusing on the evolution of endovascular thrombectomy, its impact …
Thrombo-inflammation in acute ischaemic stroke—implications for treatment
G Stoll, B Nieswandt - Nature Reviews Neurology, 2019 - nature.com
Ischaemic stroke elicits a strong neuroinflammatory response, but the functional relevance
and therapeutic potential of neuroinflammation has only recently become apparent. In acute …
and therapeutic potential of neuroinflammation has only recently become apparent. In acute …
Association between time to treatment with endovascular reperfusion therapy and outcomes in patients with acute ischemic stroke treated in clinical practice
R Jahan, JL Saver, LH Schwamm, GC Fonarow… - Jama, 2019 - jamanetwork.com
Importance Randomized clinical trials suggest benefit of endovascular-reperfusion therapy
for large vessel occlusion in acute ischemic stroke (AIS) is time dependent, but the extent to …
for large vessel occlusion in acute ischemic stroke (AIS) is time dependent, but the extent to …
Epidemiology, natural history, and clinical presentation of large vessel ischemic stroke
RC Rennert, AR Wali, JA Steinberg… - …, 2019 - journals.lww.com
Large vessel occlusions (LVOs), variably defined as blockages of the proximal intracranial
anterior and posterior circulation, account for approximately 24% to 46% of acute ischemic …
anterior and posterior circulation, account for approximately 24% to 46% of acute ischemic …