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Targeting and engineering long non-coding RNAs for cancer therapy
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
[HTML][HTML] Mechanisms of circRNA/lncRNA-miRNA interactions and applications in disease and drug research
B Ma, S Wang, W Wu, P Shan, Y Chen, J Meng… - Biomedicine & …, 2023 - Elsevier
In recent years, breakthroughs in bioinformatics have been made with the discovery of many
functionally significant non-coding RNAs (ncRNAs). The discovery of these ncRNAs has …
functionally significant non-coding RNAs (ncRNAs). The discovery of these ncRNAs has …
Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer
Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a widely
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …
Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
Iron and cancer: 2020 vision
SV Torti, FM Torti - Cancer research, 2020 - aacrjournals.org
New and provocative insights into the relationships between iron and cancer have been
uncovered in recent years. These include delineation of connections that link cellular iron to …
uncovered in recent years. These include delineation of connections that link cellular iron to …
Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
J Hou, G Zhang, X Wang, Y Wang, K Wang - Biomarker research, 2023 - Springer
Chemotherapy is one of the most important treatments for cancer therapy. However,
chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy …
chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy …
M2 Tumor‐Associated Macrophages‐Derived Exosomal MALAT1 Promotes Glycolysis and Gastric Cancer Progression
Y Wang, J Zhang, H Shi, M Wang, D Yu, M Fu… - Advanced …, 2024 - Wiley Online Library
M2‐polarized tumor‐associated macrophages (M2 TAMs) promote cancer progression.
Exosomes mediate cellular communication in the tumor microenvironment (TME). However …
Exosomes mediate cellular communication in the tumor microenvironment (TME). However …
Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p
Long noncoding RNAs (lncRNAs) have emerged as new regulatory molecules implicated in
diverse biological processes, including therapeutic resistance. However, the mechanisms …
diverse biological processes, including therapeutic resistance. However, the mechanisms …