Background The prognostic significance of insulin‐like growth factor binding protein 2
(IGFBP2) expression has been explored in plenty of studies in human cancers. Because of …

Introduction Cancer is heavily influenced by epigenetic mechanisms that include DNA
methylation, histone modifications, and non-coding RNA. A considerable proportion of …

Dual or multi-targets therapy targeting epidermal growth factor receptor variant III (EGFRvIII)
and other molecular may relax the constraint for glioblastoma (GBM), putting forward the …

Purpose. To assess the expression of insulin‐like growth factor binding protein (IGFBP)
family and its prognostic impact in ovarian cancer (OC) patients. Materials and Methods. The …

The aim of this work was to assess the cytotoxicity, genotoxicity, and histopathological
effects of Fe2O3@ Au-FA NPs using in vitro and in vivo models. Cytotoxicity and cellular …

Background Glioblastoma (GBM) is the most common primary malignant brain tumor in
adults with a poor prognosis. DEPDC1B (DEP domain-containing protein 1B) has been …

Gain-of-function point mutations in the receptor tyrosine kinase RET, a driver oncogene in
medullary thyroid carcinoma (MTC), prevent apoptosis through inhibition of ATF4, a critical …

The identification of cancer subtypes is of great importance for understanding the
heterogeneity of tumors and providing patients with more accurate diagnoses and …

IGFBP-3 is aberrantly expressed in many tumor types, and its serum and tumor tissue levels
provide auxiliary information for assessing the degree of tumor malignancy and patient …

Background It has been reported that the single nucleotide polymorphism (SNP) rs2854744
at the− 202 locus of insulin-like growth factor binding protein-3 (IGFBP3) is associated with …