Abstract The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription
factor that plays a major role in metabolic regulation. This review addresses the functional …

Non‐alcoholic fatty liver disease (NAFLD) represents a histological spectrum of liver disease
associated with obesity, diabetes and insulin resistance that extends from isolated steatosis …

Genome sequencing projects have ushered biological research into a new age where
scientists are confronted with the daunting undertaking of assigning functions to the full …

This review summarizes key aspects of what has been learned about the physiology of
leptin deficiency as it can be observed in obese‐hyperglycemic ob/ob mice. These mice lack …

While traditional nutrition research has dealt with providing nutrients to nourish populations,
it nowadays focuses on improving health of individuals through diet. Modern nutritional …

Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …

Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease in the US
and refers to a wide spectrum of liver damage, including simple steatosis, steatohepatitis …

Ornithine transcarbamylase (OTC; EC 2.1. 3.3) is a ubiquitous enzyme found in almost all
organisms, including vertebrates, microorganisms, and plants. Anabolic, mostly trimeric …

We have developed an integrated suite of algorithms, statistical methods, and computer
applications to support large-scale LC-MS-based gel-free shotgun profiling of complex …

While dietary habits continue to surface as a significant factor that may influence cancer
incidence and tumor behavior, there is considerable scientific uncertainty about who will …