Improving cancer immunotherapy by cell membrane‐camouflaged nanoparticles
Cancer immunotherapy has received tremendous attention in the past decade owing to its
clinical successes with the use of immune‐checkpoint inhibition and chimeric antigen …
clinical successes with the use of immune‐checkpoint inhibition and chimeric antigen …
Controlling natural killer cell responses: integration of signals for activation and inhibition
Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …
in the absence of antigen-specific receptors has been a challenge, but recent work has …
Natural killer cell cytotoxicity and its regulation by inhibitory receptors
S Kumar - Immunology, 2018 - Wiley Online Library
Natural killer (NK) cells express an array of germ‐line encoded receptors that are capable of
triggering cytotoxicity. NK cells tend to express many members of a given family of signalling …
triggering cytotoxicity. NK cells tend to express many members of a given family of signalling …
Mesenchymal stem cells inhibit natural killer–cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2, 3-dioxygenase and prostaglandin E2
Recently, a number of clinical trials used either mesenchymal stem cells (MSCs) or natural
killer (NK) cells in an attempt to improve the effectiveness of hematopoietic stem cell …
killer (NK) cells in an attempt to improve the effectiveness of hematopoietic stem cell …
Human NK cell education by inhibitory receptors for MHC class I
N Anfossi, P André, S Guia, CS Falk, S Roetynck… - Immunity, 2006 - cell.com
Natural killer (NK) cells recognize the absence of self MHC class I as a way to discriminate
normal cells from cells in distress. In humans, this" missing self" recognition is ensured by …
normal cells from cells in distress. In humans, this" missing self" recognition is ensured by …
Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell …
In recent years, mesenchymal stem cells (MSCs) have been shown to inhibit T-lymphocyte
proliferation induced by alloantigens or mitogens. However, no substantial information is …
proliferation induced by alloantigens or mitogens. However, no substantial information is …
Maturation of mouse NK cells is a 4-stage developmental program
L Chiossone, J Chaix, N Fuseri, C Roth… - Blood, The Journal …, 2009 - ashpublications.org
Surface density of CD27 and CD11b subdivides mouse natural killer (NK) cells into 4
subsets: CD11blowCD27low, CD11blowCD27high, CD11bhighCD27high, and …
subsets: CD11blowCD27low, CD11blowCD27high, CD11bhighCD27high, and …
MHC class I molecules and KIRs in human history, health and survival
P Parham - Nature reviews immunology, 2005 - nature.com
MHC class I molecules are ligands for the killer-cell immunoglobulin-like receptors (KIRs),
which are expressed by natural killer cells and T cells. The interactions between these …
which are expressed by natural killer cells and T cells. The interactions between these …
Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
Freshly isolated, resting natural killer (NK) cells are generally less lytic against target cells
than in vitro interleukin 2 (IL-2)-activated NK cells. To investigate the basis for this difference …
than in vitro interleukin 2 (IL-2)-activated NK cells. To investigate the basis for this difference …
Influence of diabetes mellitus on immunity to human tuberculosis
Type 2 diabetes mellitus (DM) is a major risk factor for the development of active pulmonary
tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic …
tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic …