Organoids: a novel modality in disease modeling
Limitations of monolayer culture conditions have motivated scientists to explore new models
that can recapitulate the architecture and function of human organs more accurately. Recent …
that can recapitulate the architecture and function of human organs more accurately. Recent …
Neural stem cell therapy—Brief review
C Grochowski, E Radzikowska… - Clinical neurology and …, 2018 - Elsevier
Adult mammalian neural stem cells are unique because of their properties, such as
differentiation capacity, self-renewal, quiescence, and also because they exist in specific …
differentiation capacity, self-renewal, quiescence, and also because they exist in specific …
Graphene nanomaterials as biocompatible and conductive scaffolds for stem cells: impact for tissue engineering and regenerative medicine
F Menaa, A Abdelghani… - Journal of tissue …, 2015 - Wiley Online Library
The discovery of the interesting intrinsic properties of graphene, a two‐dimensional
nanomaterial, has boosted further research and development for various types of …
nanomaterial, has boosted further research and development for various types of …
Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT
Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional
Amerindian medicine recently associated with cognitive gains, antidepressant effects, and …
Amerindian medicine recently associated with cognitive gains, antidepressant effects, and …
Engineering bone tissue from human embryonic stem cells
D Marolt, IM Campos, S Bhumiratana… - Proceedings of the …, 2012 - National Acad Sciences
In extensive bone defects, tissue damage and hypoxia lead to cell death, resulting in slow
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …
Substrate topography and size determine the fate of human embryonic stem cells to neuronal or glial lineage
S Ankam, M Suryana, LY Chan, AAK Moe, BKK Teo… - Acta biomaterialia, 2013 - Elsevier
Efficient derivation of neural cells from human embryonic stem cells (hESCs) remains an
unmet need for the treatment of neurological disorders. The limiting factors for current …
unmet need for the treatment of neurological disorders. The limiting factors for current …
Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery …
T Yuan, W Liao, NH Feng, YL Lou, X Niu… - Stem cell research & …, 2013 - Springer
Introduction Stroke is a major cause of permanent neurologic damage, with few effective
treatments available to restore lost function. Induced pluripotent stem cells (iPSCs) have the …
treatments available to restore lost function. Induced pluripotent stem cells (iPSCs) have the …
Embryonic origins of human vascular smooth muscle cells: implications for in vitro modeling and clinical application
Vascular smooth muscle cells (SMCs) arise from multiple origins during development,
raising the possibility that differences in embryological origins between SMCs could …
raising the possibility that differences in embryological origins between SMCs could …
Neural differentiation of human embryonic stem cells
Availability of human embryonic stem cells (hESC) has enhanced human neural
differentiation research. The derivation of neural progenitor (NP) cells from hESC facilitates …
differentiation research. The derivation of neural progenitor (NP) cells from hESC facilitates …
Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation
L D'Aiuto, Y Zhi, D Kumar Das, MR Wilcox… - …, 2014 - Taylor & Francis
Induced pluripotent stem cell (iPSC)-based technologies offer an unprecedented opportunity
to perform high-throughput screening of novel drugs for neurological and …
to perform high-throughput screening of novel drugs for neurological and …