Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization
Enzyme immobilization has been develo** since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …
biocatalytic processes use the technology to improve enzyme performance, still today we …
Toolbox for distal C–H bond functionalizations in organic molecules
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …
C–H activation
Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …
for molecular syntheses, enabling applications to natural product syntheses, late-stage …
C–H activation: toward sustainability and applications
T Dalton, T Faber, F Glorius - ACS Central Science, 2021 - ACS Publications
Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …
chemists have become increasingly mindful of the need to conserve natural resources and …
C–H deuteration of organic compounds and potential drug candidates
C–H deuteration has been intricately developed to satisfy the urgent need for site-selectively
deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope …
deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope …
Bidentate directing groups: an efficient tool in C–H bond functionalization chemistry for the expedient construction of C–C bonds
S Rej, Y Ano, N Chatani - Chemical reviews, 2020 - ACS Publications
During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …
New strategies for the transition-metal catalyzed synthesis of aliphatic amines
A Trowbridge, SM Walton, MJ Gaunt - Chemical reviews, 2020 - ACS Publications
Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …
simple, readily available feedstocks have become a cornerstone of modern synthetic …
N-Heterocyclic carbene complexes in C–H activation reactions
In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …
Organic synthesis with the most abundant transition metal–iron: from rust to multitasking catalysts
In industries and academic laboratories, several late transition metal-catalyzed prerequisite
reactions are widely performed during single and multistep synthesis. However, besides the …
reactions are widely performed during single and multistep synthesis. However, besides the …
3d transition metals for C–H activation
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …
notable applications to material sciences, crop protection, drug discovery, and …