Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

G Jia, Y Han, Y An, Y Ding, C He, X Wang, Q Tang - Biomaterials, 2018 - Elsevier
Currently, glioma treatment is limited by two main factors: timely detection at onset or relapse
and restriction of drugs by the blood–brain barrier (BBB) from entering the brain and …

Photodynamic therapy for glioblastoma: illuminating the path toward clinical applicability

D Bhanja, H Wilding, A Baroz, M Trifoi, G Shenoy… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common adult brain cancer. Despite
extensive treatment protocols, all glioblastomas are eventually fatal. Photodynamic therapy …

Anticancer mechanism of curcumin on human glioblastoma

SC Wong, MNA Kamarudin, R Naidu - Nutrients, 2021 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain
tumors. Current available treatment options for GBM are multimodal, which include surgical …

Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies

J **g, Z Wu, J Wang, G Luo, H Lin, Y Fan… - Signal Transduction and …, 2023 - nature.com
The past decade has seen significant advances in our understanding of Hedgehog (HH)
signaling pathway in various biological events. HH signaling pathway exerts its biological …

[HTML][HTML] Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas

A Zanotto-Filho, E Braganhol, K Klafke, F Figueiró… - Cancer letters, 2015 - Elsevier
Glioblastoma is a devastating primary brain tumor resistant to conventional therapies. In this
study, we tested the efficacy of combining temozolomide with curcumin, a phytochemical …

Curcumin-based nanomedicines: A promising avenue for brain neoplasm therapy

M Banazadeh, B Behnam, NA Ganjooei… - Journal of Drug Delivery …, 2023 - Elsevier
Brain tumor ranks as the tenth most common cause of death among individuals with cancer
globally, and those diagnosed with this condition continue to experience unfavorable …

Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

C Rajagopal, MB Lankadasari, JM Aranjani… - Pharmacological …, 2018 - Elsevier
Inflammation is one of the major causative factor of cancer and chronic inflammation is
involved in all the major steps of cancer initiation, progression metastasis and drug …

Nano-delivery systems for encapsulation of dietary polyphenols: An experimental approach for neurodegenerative diseases and brain tumors

T Squillaro, A Cimini, G Peluso, A Giordano… - Biochemical …, 2018 - Elsevier
Neurodegenerative diseases (NDs) and brain tumors are severe, disabling, and incurable
disorders that represent a critical problem regarding human suffering and the economic …