Complex post-traumatic stress disorder (complex PTSD) is a severe mental disorder that
emerges in response to traumatic life events. Complex PTSD is characterised by three core …

This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Importance Exposure to adverse childhood experiences (ACEs) has consistently been
associated with multiple negative mental health outcomes extending into adulthood …

Background Major depressive disorder (MDD) and generalized anxiety disorder (GAD) are
leading causes of disability and premature mortality. At a global level, over 300 million …

Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

Abstract Background The Center for Disease Control (CDC) and Kaiser Permanente
developed the Adverse Childhood Experiences (ACE) scale to identify negative experiences …

Attention to childhood trauma and the need for trauma-informed care has contributed to the
emerging discourse in schools related to teaching practices, school climate, and the delivery …

A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …

Abstract Adverse Childhood Experiences (ACEs) are stressful and/or traumatic experiences
associated with an increased lifetime risk of negative health outcomes. The Allostatic Load …