COVID‐19 and toll‐like receptor 4 (TLR4): SARS‐CoV‐2 may bind and activate TLR4 to increase ACE2 expression, facilitating entry and causing hyperinflammation
MM Aboudounya, RJ Heads - Mediators of inflammation, 2021 - Wiley Online Library
Causes of mortality from COVID‐19 include respiratory failure, heart failure, and
sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that …
sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that …
DNA vaccines against COVID-19: Perspectives and challenges
MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus known
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …
A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study
A new strain of a novel infectious disease affecting millions of people, caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been declared as a …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been declared as a …
Using X-ray images and deep learning for automated detection of coronavirus disease
K El Asnaoui, Y Chawki - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Coronavirus is still the leading cause of death worldwide. There are a set number of COVID-
19 test units accessible in emergency clinics because of the expanding cases daily …
19 test units accessible in emergency clinics because of the expanding cases daily …
SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective
AA Elfiky - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
New treatment against SARS-CoV-2 now is a must. Nowadays, the world encounters a huge
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …
A molecular modeling approach to identify effective antiviral phytochemicals against the main protease of SARS-CoV-2
The main protease of SARS-CoV-2 is one of the important targets to design and develop
antiviral drugs. In this study, we have selected 40 antiviral phytochemicals to find out the …
antiviral drugs. In this study, we have selected 40 antiviral phytochemicals to find out the …
Stilbene-based natural compounds as promising drug candidates against COVID-19
The pandemic coronavirus disease (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently …
syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently …
COVID-19: Advances in diagnostic tools, treatment strategies, and vaccine development
An unprecedented worldwide spread of the SARS-CoV-2 has imposed severe challenges
on healthcare facilities and medical infrastructure. The global research community faces …
on healthcare facilities and medical infrastructure. The global research community faces …
Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …