A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Bearing my heart: the role of extracellular matrix on cardiac development, homeostasis, and injury response

AC Silva, C Pereira, ACRG Fonseca… - Frontiers in Cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an essential component of the heart that imparts
fundamental cellular processes during organ development and homeostasis. Most …

Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury

Z Álvarez, AN Kolberg-Edelbrock, IR Sasselli… - Science, 2021 - science.org
The signaling of cells by scaffolds of synthetic molecules that mimic proteins is known to be
effective in the regeneration of tissues. Here, we describe peptide amphiphile …

[HTML][HTML] Cardioids reveal self-organizing principles of human cardiogenesis

P Hofbauer, SM Jahnel, N Papai, M Giesshammer… - Cell, 2021 - cell.com
Organoids capable of forming tissue-like structures have transformed our ability to model
human development and disease. With the notable exception of the human heart, lineage …

Proteins and peptides as important modifiers of the polymer scaffolds for tissue engineering applications—a review

K Klimek, G Ginalska - Polymers, 2020 - mdpi.com
Polymer scaffolds constitute a very interesting strategy for tissue engineering. Even though
they are generally non-toxic, in some cases, they may not provide suitable support for cell …

The human epidermal basement membrane: a shaped and cell instructive platform that aging slowly alters

E Roig-Rosello, P Rousselle - Biomolecules, 2020 - mdpi.com
One of the most important functions of skin is to act as a protective barrier. To fulfill this role,
the structural integrity of the skin depends on the dermal-epidermal junction—a complex …

Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids

V Hernandez-Gordillo, T Kassis, A Lampejo, GH Choi… - Biomaterials, 2020 - Elsevier
Epithelial organoids derived from human donor tissues are important tools in fields ranging
from regenerative medicine to drug discovery. Organoid culture requires expansion of …

Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche

SC Schüler, Y Liu, S Dumontier… - Frontiers in Cell and …, 2022 - frontiersin.org
The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

3D bioprinted vascularized lung cancer organoid models with underlying disease capable of more precise drug evaluation

Y Choi, H Lee, M Ann, M Song, J Rheey, J Jang - Biofabrication, 2023 - iopscience.iop.org
Despite encouraging progress in the development of in vitro cancer models, in vitro cancer
models that simultaneously recapitulate the complexity of the tumor microenvironment and …

Extracellular matrix-based biomaterials for cardiovascular tissue engineering

A Khanna, M Zamani, NF Huang - Journal of cardiovascular development …, 2021 - mdpi.com
Regenerative medicine and tissue engineering strategies have made remarkable progress
in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of …