The past 40 years have witnessed extensive research on fractal structure and scale-free
dynamics in the brain. Although considerable progress has been made, a comprehensive …

Tissue clearing increases the transparency of late developmental stages and enables deep
imaging in fixed organisms. Successful implementation of these methodologies requires a …

INTRODUCTION The brains of extant animals have evolved over hundreds of millions of
years from simple circuits. Cell types diversified, connections elaborated, and new brain …

Whole-brain mesoscale map** in primates has been hindered by large brain sizes and
the relatively low throughput of available microscopy methods. Here, we present an …

Whole-brain analysis of single-neuron morphology is crucial for unraveling the complex
structure of the brain. However, large-scale neuron reconstruction from terabyte and even …

Recent proliferation and integration of tissue-clearing methods and light-sheet fluorescence
microscopy has created new opportunities to achieve mesoscale three-dimensional whole …

Food intake and body weight are tightly regulated by neurons within specific brain regions,
including the brainstem, where acute activation of dorsal raphe nucleus (DRN) …

Optimizing reproductive fitness in mammalians requires behavioral adaptations during
pregnancy. Maternal preparatory nesting is an essential behavior for the survival of the …

Neuronal activity plays a critical role in the maturation of circuits that propagate sensory
information into the brain. How widely does early activity regulate circuit maturation across …

Antibodies have diverse applications due to their high reaction specificities but are sensitive
to denaturation when a higher working temperature is required. We have developed a …