[HTML][HTML] How are hydrogen peroxide messages relayed to affect cell signalling?

EA Veal, P Kritsiligkou - Current opinion in chemical biology, 2024 - Elsevier
H 2 O 2 signals trigger adaptive responses affecting cell division, differentiation, migration,
and survival. These signals are transduced by selective oxidation of cysteines on specific …

The multifaceted nature of peroxiredoxins in chemical biology

SF Villar, G Ferrer-Sueta, A Denicola - Current opinion in chemical biology, 2023 - Elsevier
Abstract Peroxiredoxins (Prx), thiol-dependent peroxidases, were first identified as H 2 O 2
detoxifiers, and more recently as H 2 O 2 sensors, intermediates in redox-signaling …

Macrophages: shapes and functions

U Lendeckel, S Venz, C Wolke - ChemTexts, 2022 - Springer
Macrophages are cells of the innate immune system and represent an important component
of the first-line defense against pathogens and tumor cells. Here, their diverse functions in …

The footprint of kynurenine pathway in cardiovascular diseases

M Ala, SP Eftekhar - International Journal of Tryptophan …, 2022 - journals.sagepub.com
Kynurenine pathway is the main route of tryptophan metabolism and produces several
metabolites with various biologic properties. It has been uncovered that several …

Removal of Microcystis aeruginosa and microcystin-LR by UV/Fenton system: Characteristics and degradation pathways

X Ma, J Chen, B Liu, Y Huang, Y Tang, Q Wei - Separation and Purification …, 2023 - Elsevier
The increasing severity of cyanobacterial blooms owing to eutrophication in water bodies
has caused widespread concern. In this study, the UV/Fenton system was evaluated for the …

[HTML][HTML] How abundant are superoxide and hydrogen peroxide in the vasculature lumen, how far can they reach?

T Sousa, M Gouveia, RDM Travasso, A Salvador - Redox Biology, 2022 - Elsevier
Abstract Paracrine superoxide (O 2•−) and hydrogen peroxide (H 2 O 2) signaling critically
depends on these substances' concentrations, half-lives and transport ranges in …

Increased Tryptophan Catabolism Provides Predictive Value to Chronic Heart Failure Patients with Low-Grade Inflammation

H Wang, J Wu, H Wei, Y Zhang, Y Wang, DW Wang - Inflammation, 2024 - Springer
Kynurenine to tryptophan ratio (KTR), which serves as an indicator for evaluating
indoleamine-2, 3-dioxygenase activity and inflammation, has been reported to be linked with …

[HTML][HTML] The architecture of redox microdomains: Cascading gradients and peroxiredoxins' redox-oligomeric coupling integrate redox signaling and antioxidant …

M Griffith, A Araújo, R Travasso, A Salvador - Redox Biology, 2024 - Elsevier
In the cytosol of human cells under low oxidative loads, hydrogen peroxide is confined to
microdomains around its supply sites, due to its fast consumption by peroxiredoxins. So are …

Exploring functional and structural features of chemically related natural prenylated hydroquinone and benzoic acid from Piper crassinervium (Piperaceae) on …

VI Montanhero Cabrera, G do Nascimento Sividanes… - Plos one, 2023 - journals.plos.org
Multiple drug resistance (MDR) bacterial strains are responsible by 1.2 million of human
deaths all over the world. The pathogens possess efficient enzymes which are able to …

Comparison of Hydrogen Peroxide Secretion from Living Cells Cultured in Different Formats Using Hydrogel-Based LSPR Substrates

YJ Siao, CC Peng, YC Tung, YF Chen - Frontiers in bioengineering …, 2022 - frontiersin.org
Reactive oxygen species (ROS), a number of reactive molecules and free radicals derived
from molecular oxygen, are generated as by-products during mitochondrial electron …