Phase reduction and phase-based optimal control for biological systems: a tutorial

B Monga, D Wilson, T Matchen, J Moehlis - Biological cybernetics, 2019 - Springer
A powerful technique for the analysis of nonlinear oscillators is the rigorous reduction to
phase models, with a single variable describing the phase of the oscillation with respect to …

Control and synchronization of neuron ensembles

JS Li, I Dasanayake, J Ruths - IEEE Transactions on automatic …, 2013 - ieeexplore.ieee.org
Synchronization of oscillations is a phenomenon prevalent in natural, social, and
engineering systems. Controlling synchronization of oscillating systems is motivated by a …

Inferring dynamic topology for decoding spatiotemporal structures in complex heterogeneous networks

S Wang, ED Herzog, IZ Kiss… - Proceedings of the …, 2018 - National Acad Sciences
Extracting complex interactions (ie, dynamic topologies) has been an essential, but difficult,
step toward understanding large, complex, and diverse systems including biological …

Minimum energy desynchronizing control for coupled neurons

A Nabi, M Mirzadeh, F Gibou, J Moehlis - Journal of computational …, 2013 - Springer
We employ optimal control theory to design an event-based, minimum energy,
desynchronizing control stimulus for a network of pathologically synchronized …

Optimal entrainment of neural oscillator ensembles

A Zlotnik, JS Li - Journal of neural engineering, 2012 - iopscience.iop.org
In this paper, we derive the minimum-energy periodic control that entrains an ensemble of
structurally similar neural oscillators to a desired frequency. The state-space representation …

Single input optimal control for globally coupled neuron networks

A Nabi, J Moehlis - Journal of neural engineering, 2011 - iopscience.iop.org
We consider the problem of desynchronizing a network of synchronized, globally (all-to-all)
coupled neurons using an input to a single neuron. This is done by applying the discrete …

Minimum energy control for in vitro neurons

A Nabi, T Stigen, J Moehlis… - Journal of neural …, 2013 - iopscience.iop.org
Objective. To demonstrate the applicability of optimal control theory for designing minimum
energy charge-balanced input waveforms for single periodically-firing in vitro neurons from …

Time optimal control of spiking neurons

A Nabi, J Moehlis - Journal of mathematical biology, 2012 - Springer
By injecting an electrical current control stimulus into a neuron, one can change its inter-
spike intervals. In this paper, we investigate the time optimal control problem for periodically …

Engineering spatiotemporal patterns: information encoding, processing, and controllability in oscillator ensembles

W Bomela, B Singhal, JS Li - Biomedical Physics & Engineering …, 2023 - iopscience.iop.org
The ability to finely manipulate spatiotemporal patterns displayed in neuronal populations is
critical for understanding and influencing brain functions, sleep cycles, and neurological …

[PDF][PDF] Charge-balanced spike timing control for phase models of spiking neurons

P Danzl, A Nabi, J Moehlis - Discrete and Continuous Dynamical …, 2010 - researchgate.net
This paper explores event-based feedback schemes for controlling spike timing in phase
models of neurons with the constraint of a chargebalanced stimulus over a period of …