[HTML][HTML] Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle

G Sahana, Z Cai, MP Sanchez, AC Bouwman… - Journal of Dairy …, 2023 - Elsevier
Genotype data from dairy cattle selection programs have greatly facilitated GWAS to identify
variants related to economic traits. Results can enhance the accuracy of genomic prediction …

[HTML][HTML] Underlying genetic architecture of resistance to mastitis in dairy cattle: A systematic review and gene prioritization analysis of genome-wide association …

SG Narayana, E de Jong, FS Schenkel… - Journal of Dairy …, 2023 - Elsevier
Mastitis, the most frequent disease in dairy cattle. Resistance to mastitis is a complex,
polygenic trait controlled by several genes, each with small effects. Genome-wide …

Meta-analysis of six dairy cattle breeds reveals biologically relevant candidate genes for mastitis resistance

Z Cai, T Iso-Touru, MP Sanchez, N Kadri… - Genetics Selection …, 2024 - Springer
Background Mastitis is a disease that incurs significant costs in the dairy industry. A
promising approach to mitigate its negative effects is to genetically improve the resistance of …

Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

T Tribout, P Croiseau, R Lefebvre, A Barbat… - Genetics Selection …, 2020 - Springer
Background Over the last years, genome-wide association studies (GWAS) based on
imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci …

Genome-wide association study for udder conformation traits in Chinese Holstein cattle

M Nazar, IM Abdalla, Z Chen, N Ullah, Y Liang, S Chu… - Animals, 2022 - mdpi.com
Simple Summary Udder conformation traits are economically important for dairy animals in
the dairy industry. Milk production loss can be reduced via a better udder structure in dairy …

A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle

YL Lee, H Takeda, G Costa Monteiro Moreira… - PLoS …, 2021 - journals.plos.org
Clinical mastitis (CM) is an inflammatory disease occurring in the mammary glands of
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …

Prioritizing candidate genes for fertility in dairy cows using gene-based analysis, functional annotation and differential gene expression

Z Cai, B Guldbrandtsen, MS Lund, G Sahana - BMC genomics, 2019 - Springer
Background An unfavorable genetic correlation between milk production and fertility makes
simultaneous improvement of milk production and fertility difficult in cattle breeding. Rapid …

[HTML][HTML] Genome-wide association and functional genomic analyses for various hoof health traits in North American Holstein cattle

LPBS Junior, LFB Pinto, VAR Cruz, GA Oliveira Jr… - Journal of Dairy …, 2024 - Elsevier
Hoof diseases are a major welfare and economic issue in the global dairy cattle production
industry, which can be minimized through improved management and breeding practices …

[HTML][HTML] A genomic assessment of the correlation between milk production traits and claw and udder health traits in Holstein dairy cattle

H Schneider, D Segelke, J Tetens, G Thaller… - Journal of dairy …, 2023 - Elsevier
Claw diseases and mastitis represent the most important disease traits in dairy cattle with
increasing incidences and a frequently mentioned connection to milk yield. Yet, many …

Genetic parameters and genome-wide association studies of eight longevity traits representing either full or partial lifespan in Chinese Holsteins

H Zhang, A Liu, Y Wang, H Luo, X Yan, X Guo… - Frontiers in …, 2021 - frontiersin.org
Due to the complexity of longevity trait in dairy cattle, two groups of trait definitions are widely
used to measure longevity, either covering the full lifespan or representing only a part of it to …