As the gap between donors and patients in need of an organ transplant continues to widen,
research in regenerative medicine seeks to provide alternative strategies for treatment. One …

Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …

In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Abstract 3D printing technique is the most sophisticated technique to produce scaffolds with
tailorable physical properties. But, these scaffolds often suffer from limited biological …

Stem cells have emerged as a key element of regenerative medicine therapies due to their
inherent ability to differentiate into a variety of cell phenotypes, thereby providing numerous …

The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Recent advances in understanding the cellular and molecular signaling pathways and
global transcriptional regulators of adult mesenchymal stem cells have provided new …

Critical sized bone defects have to be filled with material to allow bone healing. The golden
standard for this treatment is autogenous bone grafting. Because of donor size morbidity …

Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …