EANO guideline on the diagnosis and treatment of vestibular schwannoma

R Goldbrunner, M Weller, J Regis… - Neuro …, 2020‏ - academic.oup.com
The level of evidence to provide treatment recommendations for vestibular schwannoma is
low compared with other intracranial neoplasms. Therefore, the vestibular schwannoma task …

Malignant peripheral nerve sheath tumor: models, biology, and translation

BN Somatilaka, A Sadek, RM McKay, LQ Le - Oncogene, 2022‏ - nature.com
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, invasive cancer that
comprise around 10% of all soft tissue sarcomas and develop in about 8–13% of patients …

Malignant peripheral nerve sheath tumors: latest concepts in disease pathogenesis and clinical management

C Yao, H Zhou, Y Dong, A Alhaskawi… - Cancers, 2023‏ - mdpi.com
Simple Summary Malignant peripheral nerve sheath tumor (MPNST) is a soft tissue sarcoma
with limited therapeutic interventions and a poor prognosis. This review summarized the …

[HTML][HTML] Molecular pathology of tumors of the central nervous system

BW Kristensen, LP Priesterbach-Ackley, JK Petersen… - Annals of oncology, 2019‏ - Elsevier
Since the update of the 4th edition of the WHO Classification of Central Nervous System
(CNS) Tumors published in 2016, particular molecular characteristics are part of the …

Diagnostic pathology of tumors of peripheral nerve

SM Belakhoua, FJ Rodriguez - Neurosurgery, 2021‏ - journals.lww.com
Neoplasms of the peripheral nervous system represent a heterogenous group with a wide
spectrum of morphological features and biological potential. They range from benign and …

Histopathologic evaluation of atypical neurofibromatous tumors and their transformation into malignant peripheral nerve sheath tumor in patients with …

MM Miettinen, CR Antonescu, CDM Fletcher, A Kim… - Human pathology, 2017‏ - Elsevier
Summary Patients with neurofibromatosis 1 (NF1) develop multiple neurofibromas, with 8%
to 15% of patients experiencing malignant peripheral nerve sheath tumor (MPNST) during …

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

M Röhrich, C Koelsche, D Schrimpf, D Capper… - Acta …, 2016‏ - Springer
The vast majority of peripheral nerve sheath tumors derive from the Schwann cell lineage
and comprise diverse histological entities ranging from benign schwannomas and …

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

AHG Cleven, GA Al Sannaa, I Briaire-de Bruijn… - Modern …, 2016‏ - nature.com
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that can
show overlap** features with benign neurofibromas as well as high-grade sarcomas …

[PDF][PDF] Diagnosis and management of malignant peripheral nerve sheath tumors: Current practice and future perspectives

BC Prudner, T Ball, R Rathore… - Neuro-Oncology …, 2020‏ - academic.oup.com
One of the most common malignancies affecting adults with the neurofibromatosis type 1
(NF1) cancer predisposition syndrome is the malignant peripheral nerve sheath tumor …

Malignant peripheral nerve sheath tumors state of the science: leveraging clinical and biological insights into effective therapies

AR Kim, DR Stewart, KM Reilly, D Viskochil… - Sarcoma, 2017‏ - Wiley Online Library
Malignant peripheral nerve sheath tumor (MPNST) is the leading cause of mortality in
patients with neurofibromatosis type 1. In 2002, an MPNST consensus statement reviewed …