[HTML][HTML] Biomarkers of aging for the identification and evaluation of longevity interventions
With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …
longevity interventions in humans have become key goals of this field. Biomarkers of aging …
Mechanisms of sex differences in Alzheimer's disease
C Lopez-Lee, ERS Torres, G Carling, L Gan - Neuron, 2024 - cell.com
Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …
complex and multifactorial. The higher AD risk in women may serve as a clue to better …
Assessing the risk of cervical neoplasia in the post‐HPV vaccination era
This review is based on the recent EUROGIN scientific session:“Assessing risk of cervical
cancer in the post‐vaccination era,” which addressed the demands of cervical intraepithelial …
cancer in the post‐vaccination era,” which addressed the demands of cervical intraepithelial …
A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes
Background Changes in cell-type composition of tissues are associated with a wide range of
diseases and environmental risk factors and may be causally implicated in disease …
diseases and environmental risk factors and may be causally implicated in disease …
Cigarette smoking and e-cigarette use induce shared DNA methylation changes linked to carcinogenesis
Tobacco use is a major modifiable risk factor for adverse health outcomes, including cancer,
and elicits profound epigenetic changes thought to be associated with long-term cancer risk …
and elicits profound epigenetic changes thought to be associated with long-term cancer risk …
The WID‐EC test for the detection and risk prediction of endometrial cancer
The incidence of endometrial cancer is rising. Measures to identify women at risk and to
detect endometrial cancer earlier are required to reduce the morbidity triggered by the …
detect endometrial cancer earlier are required to reduce the morbidity triggered by the …
Associations of biological age accelerations and genetic risk with incident endometrial cancer: a prospective analysis in UK Biobank
Z Yang, Y Shen, T Zhang, X Tang… - International Journal of …, 2025 - journals.lww.com
Background: Endometrial cancer (EC) is one of the gynecologic malignancy cancer with
increasing incidence and mortality rates, partly due to aging populations and genetic risks …
increasing incidence and mortality rates, partly due to aging populations and genetic risks …
Devising reliable and accurate epigenetic predictors: choosing the optimal computational solution
Illumina DNA methylation arrays are frequently used for the discovery of methylation
signatures associated with aging and disease. One of the major hurdles to overcome when …
signatures associated with aging and disease. One of the major hurdles to overcome when …
Technical and biological sources of unreliability of Infinium probes on Illumina Methylation microarrays
ABSTRACT The Illumina Methylation array platform has facilitated countless epigenetic
studies on DNA methylation (DNAme) in health and disease, yet relatively few studies have …
studies on DNA methylation (DNAme) in health and disease, yet relatively few studies have …