MicroRNAs: from mechanism to organism
PJ Dexheimer, L Cochella - Frontiers in cell and developmental …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …
Small and long non-coding RNAs: Past, present, and future
LL Chen, VN Kim - Cell, 2024 - cell.com
Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
An integrated expression atlas of miRNAs and their promoters in human and mouse
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …
The molecular evolution of spermatogenesis across mammals
The testis produces gametes through spermatogenesis and evolves rapidly at both the
morphological and molecular level in mammals,,,,–, probably owing to the evolutionary …
morphological and molecular level in mammals,,,,–, probably owing to the evolutionary …
Structural and functional basis of mammalian microRNA biogenesis by Dicer
D Zapletal, E Taborska, J Pasulka, R Malik, K Kubicek… - Molecular cell, 2022 - cell.com
MicroRNA (miRNA) and RNA interference (RNAi) pathways rely on small RNAs produced by
Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating …
Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating …
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate-and tissue-specific microRNAs
E Londin, P Loher, AG Telonis… - Proceedings of the …, 2015 - National Acad Sciences
Two decades after the discovery of the first animal microRNA (miRNA), the number of
miRNAs in animal genomes remains a vexing question. Here, we report findings from …
miRNAs in animal genomes remains a vexing question. Here, we report findings from …
A uniform system for the annotation of vertebrate microRNA genes and the evolution of the human microRNAome
Although microRNAs (miRNAs) are among the most intensively studied molecules of the
past 20 years, determining what is and what is not a miRNA has not been straightforward …
past 20 years, determining what is and what is not a miRNA has not been straightforward …
Comparative transcriptomics in human and mouse
Cross-species comparisons of genomes, transcriptomes and gene regulation are now
feasible at unprecedented resolution and throughput, enabling the comparison of human …
feasible at unprecedented resolution and throughput, enabling the comparison of human …
The roles of microRNAs in mouse development
B DeVeale, J Swindlehurst-Chan… - Nature Reviews Genetics, 2021 - nature.com
Hundreds of microRNAs (miRNAs) are expressed in distinct spatial and temporal patterns
during embryonic and postnatal mouse development. The loss of all miRNAs through the …
during embryonic and postnatal mouse development. The loss of all miRNAs through the …
A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription
A comprehensive transcriptomic survey of pigs can provide a mechanistic understanding of
tissue specialization processes underlying economically valuable traits and accelerate their …
tissue specialization processes underlying economically valuable traits and accelerate their …