Return of individual research results from genomic research: A systematic review of stakeholder perspectives
Despite the plethora of empirical studies conducted to date, debate continues about whether
and to what extent results should be returned to participants of genomic research. We aimed …
and to what extent results should be returned to participants of genomic research. We aimed …
Secondary findings from whole-exome/genome sequencing evaluating stakeholder perspectives. A review of the literature
With the development of next generation sequencing, beyond identifying the cause of
manifestations that justified prescription of the test, other information with potential interest …
manifestations that justified prescription of the test, other information with potential interest …
Whether, when, how, and how much? General public's and cancer patients' views about the disclosure of genomic secondary findings
JE Cléophat, M Dorval, Z El Haffaf, J Chiquette… - BMC Medical …, 2021 - Springer
Background Data on the modalities of disclosing genomic secondary findings (SFs) remain
scarce. We explore cancer patients' and the general public's perspectives about disclosing …
scarce. We explore cancer patients' and the general public's perspectives about disclosing …
Moral duties of genomics researchers: why personalized medicine requires a collective approach
S Vos, JJM van Delden, PJ van Diest, AL Bredenoord - Trends in Genetics, 2017 - cell.com
Advances in genome sequencing together with the introduction of personalized medicine
offer promising new avenues for research and precision treatment, particularly in the field of …
offer promising new avenues for research and precision treatment, particularly in the field of …
Psychiatric genetics researchers' views on offering return of results to individual participants
In the middle of growing consensus that genomics researchers should offer to return
clinically valid, medically relevant, and medically actionable findings identified in the course …
clinically valid, medically relevant, and medically actionable findings identified in the course …
Public's views toward return of secondary results in genomic sequencing: It's (almost) all about the choice
The therapeutic use of genomic sequencing creates novel and unresolved questions about
cost, clinical efficacy, access, and the disclosure of sequencing results. The disclosure of the …
cost, clinical efficacy, access, and the disclosure of sequencing results. The disclosure of the …
Implementation of genomics in medical practice to deliver precision medicine for an Asian population
Whilst the underlying principles of precision medicine are comparable across the globe,
genomic references, health practices, costs and discrimination policies differ in Asian …
genomic references, health practices, costs and discrimination policies differ in Asian …
Discussing molecular testing in oncology care: Comparing patient and physician information preferences
APM Pinheiro, RH Pocock, JM Switchenko, MD Dixon… - Cancer, 2017 - Wiley Online Library
BACKGROUND Molecular testing to inform treatment and clinical trial choices is now the
standard of care for several types of cancer. However, no established guidelines exist for the …
standard of care for several types of cancer. However, no established guidelines exist for the …
Controversies among cancer registry participants, genomic researchers, and institutional review boards about returning participants' genomic results
KL Edwards, D Goodman, CO Johnson… - Public Health …, 2019 - karger.com
Objectives: Genomic information will increasingly be used to aid in the prevention,
diagnosis, and treatment of disease. Several national initiatives are paving the way for this …
diagnosis, and treatment of disease. Several national initiatives are paving the way for this …
Primary care provider perspectives on using genomic sequencing in the care of healthy children
E Joshi, C Mighton, M Clausen, S Casalino… - European Journal of …, 2020 - nature.com
Genome sequencing (GS) studies involving healthy children can advance scientific
knowledge of genetic variation. Little research has examined primary care providers' views …
knowledge of genetic variation. Little research has examined primary care providers' views …