Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Introduction Drugs targeting mitochondria are emerging as promising antitumor therapeutics
in preclinical models. However, a few of these drugs have shown clinical toxicity …

Simple Summary Although there are various treatments for tumors, chemotherapy is still one
of the most dominant and irreplaceable treatment modalities nowadays. Unfortunately …

Cancer chemoprevention is the most effective approach to control cancer in the population.
Despite significant progress, chemoprevention has not been widely adopted because …

Pharmacological targeting of mitochondrial ion channels is emerging as a promising
approach to eliminate cancer cells; as most of these channels are differentially expressed …

Honokiol (HNK) is a natural polyphenolic compound extracted from the bark and leaves of
Magnolia grandiflora. It has been traditionally used as a medicinal compound to treat …

Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …

Phenylbutyric acid (PBA) has been reported as a dual inhibitor of pyruvate dehydrogenase
kinases (PDKs) and histone deacetylases (HDACs), exhibiting anticancer effects. However …

Succinate dehydrogenase (SDH) is an effective target of SDH inhibitor (SDHI) fungicides
which received more and more attention in recent years. However, there is no good solution …