Human genetic determinants of viral diseases

AD Kenney, JA Dowdle, L Bozzacco… - Annual review of …, 2017 - annualreviews.org
Much progress has been made in the identification of specific human gene variants that
contribute to enhanced susceptibility or resistance to viral diseases. Herein we review …

Genomic risk factors for cervical cancer

D Ramachandran, T Dörk - Cancers, 2021 - mdpi.com
Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …

Genetic susceptibility in cervical cancer: from bench to bedside

A Bahrami, M Hasanzadeh… - Journal of cellular …, 2018 - Wiley Online Library
Cervical cancer (CC) is the third most common malignancy in women globally, and
persistent infection with the oncogenic human papillomaviruses (HPV) is recognized as the …

TNF-α and IL-10 promoter polymorphisms, HPV infection, and cervical cancer risk

G Barbisan, LO Pérez, A Contreras, CD Golijow - Tumor Biology, 2012 - Springer
Although the implication of genetic factors in cervical cancer development remains to be
elucidated, accumulative epidemiological evidence suggests that polymorphisms of cytokine …

Association of polymorphisms in cytokine genes with susceptibility to precancerous lesions and cervical cancer: a systematic review with meta-analysis

EL de Moura, ACM Dos Santos… - Immunological …, 2021 - Taylor & Francis
Objectives: This study investigated the relationship between single-nucleotide
polymorphisms (SNPs) in cytokine genes and the susceptibility to Squamous Intraepithelial …

Lessons and implications from association studies and post-GWAS analyses of cervical cancer

D Chen, U Gyllensten - Trends in Genetics, 2015 - cell.com
Cervical cancer has a heritable genetic component. A large number of genetic associations
with cervical cancer have been reported in hypothesis-driven candidate gene studies, but …

State of art of cancer pharmacogenomics in Latin American populations

A López-Cortés, S Guerrero, MA Redal… - International Journal of …, 2017 - mdpi.com
Over the past decades, several studies have shown that tumor-related somatic and germline
alterations predicts tumor prognosis, drug response and toxicity. Latin American populations …

[HTML][HTML] A meta-analysis for association of xrcc3 rs861539, mthfr rs1801133, il-6 rs1800795, il-12b rs3212227, tnf-α rs1800629, and tlr9 rs352140 polymorphisms with …

SF Parsaeian, F Asadian, M Karimi-Zarchi… - Asian Pacific journal …, 2021 - ncbi.nlm.nih.gov
Background: In spite of substantial declines in both incidence and mortality rates in the past
50 years, cervical cancer remains one of the leading causes of cancer associated mortality …

Mitochondrial DNA ancestry, HPV infection and the risk of cervical cancer in a multiethnic population of northeastern Argentina

I Badano, DJ Sanabria, ME Totaro, S Rubinstein… - PloS one, 2018 - journals.plos.org
Background Misiones Province in northeastern Argentina is considered to be a region with a
high prevalence of HPV infection and a high mortality rate due to cervical cancer. The …

The correlation between TNF-α promoter gene polymorphism and genetic susceptibility to cervical cancer

X Li, G Yin, J Li, A Wu, Z Yuan… - Technology in cancer …, 2018 - journals.sagepub.com
To investigate the association between the susceptibility to cervical cancer and the single
nucleotide polymorphisms of 5 tumor necrosis factor-α promoter genes (rs361525 …