Systemic sclerosis (SSc) is a complex autoimmune disease characterized by vascular
damage, vasoinstability, and decreased perfusion with ischemia, inflammation, and …

Autoimmune rheumatic diseases are characterised by an abnormal immune system
response, complement activation, cytokines dysregulation and inflammation. In last years …

Objective Interstitial lung disease (ILD) in systemic sclerosis (SS c) runs a highly variable
course, and prediction tools are highly desired. The aim of this study was to assess the …

Exaggerated neutrophil activation and formation of neutrophil extracellular traps (NETs) are
reported in systemic sclerosis (SSc) but its involvement in SSc pathogenesis is not clear. In …

Abstract Centromere defects in Systemic Sclerosis (SSc) have remained unexplored despite
the fact that many centromere proteins were discovered in patients with SSc. Here we report …

Objective MicroRNAs (miRNAs) are regulatory molecules, which have been addressed as
potential biomarkers and therapeutic targets in rheumatic diseases. Here, we investigated …

Introduction The identification of new, easily measurable biomarkers might assist clinicians
in diagnosing and managing systemic sclerosis (SSc). Although the full blood count is …

Objectives To mine the serum proteome of patients with systemic sclerosis-associated
pulmonary arterial hypertension (SSc-PAH) and to detect biomarkers that may assist in …

Abstract Background MicroRNA (miRNA)-21-5p participates in various biological processes,
including cancer and autoimmune diseases. However, its role in the development of fibrosis …

The discovery and validation of biomarkers resulting from technological advances in the
analysis of genomic, transcriptomic, lipidomic and metabolomic pathways involved in the …