Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Considerable development in the application of injectable drug delivery systems for cancer
therapy has occurred in the last few decades. These improvements include liposomes, lipid …

Nanoparticles with multifunctionality are being designed and formulated to overcome
various limitations of drugs as well as conventional drug delivery systems. Engineered …

Chemotherapy is the routine treatment for cancer despite the poor efficacy and associated
off‐target toxicity. Furthermore, therapeutic doses of chemotherapeutic agents are limited …

Paclitaxel (PTX) is a gold standard chemotherapeutic agent for breast, ovarian, pancreatic
and non-small cell lung carcinoma. However, in clinical use PTX can have adverse side …

Excessive activation of signal transducer and activator of transcription 3 (STAT3) signaling is
observed in a subset of many cancers, making activated STAT3 a highly promising potential …

Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) and the active
metabolite is rhein. It is a non-steroidal anti-inflammatory drug with unique pharmacological …

The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …

Among many nanoparticle-based delivery platforms, liposomes have been particularly
successful with many formulations passed into clinical applications. They are well …