Biology and therapeutic targeting of vascular endothelial growth factor A

L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

Pathological angiogenesis: mechanisms and therapeutic strategies

AC Dudley, AW Griffioen - Angiogenesis, 2023 - Springer
In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

[HTML][HTML] Manganese ferrite (MnFe2O4) nanostructures for cancer theranostics

CR Kalaiselvan, SS Laha, SB Somvanshi… - Coordination Chemistry …, 2022 - Elsevier
Over the past decade, transition metal-based ferrite nanostructures, displaying MFe 2 O 4
stoichiometry (M 2+ cations, eg, Mn, Co, Ni and Zn), have been devised and examined …

[HTML][HTML] The impact of VEGF on cancer metastasis and systemic disease

Y Yang, Y Cao - Seminars in cancer biology, 2022 - Elsevier
Metastasis is the leading cause of cancer-associated mortality and the underlying
mechanisms of cancer metastasis remain elusive. Both blood and lymphatic vasculatures …

Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

M Grunewald, S Kumar, H Sharife, E Volinsky… - Science, 2021 - science.org
INTRODUCTION All body cells rely on blood vessels (BVs) for the provision of oxygen and
other blood-borne substances and, in certain settings, also for the provision of endothelial …

Mechanisms of cancer metastasis

M Castaneda, P den Hollander, NA Kuburich… - Seminars in cancer …, 2022 - Elsevier
Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from
metastatic disease. Combating cancer metastasis and post-therapeutic recurrence …

Tissue homeostasis and inflammation

ML Meizlish, RA Franklin, X Zhou… - Annual review of …, 2021 - annualreviews.org
There is a growing interest in understanding tissue organization, homeostasis, and
inflammation. However, despite an abundance of data, the organizing principles of tissue …

Milestones in tumor vascularization and its therapeutic targeting

M De Palma, D Hanahan - Nature cancer, 2024 - nature.com
Research into the mechanisms and manifestations of solid tumor vascularization was
launched more than 50 years ago with the proposition and experimental demonstrations that …

Age-related macular degeneration

P Mitchell, G Liew, B Gopinath, TY Wong - The Lancet, 2018 - thelancet.com
Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …

Smart bioadhesives for wound healing and closure

J Zhu, H Zhou, EM Gerhard, S Zhang, FIP Rodríguez… - Bioactive Materials, 2023 - Elsevier
The high demand for rapid wound healing has spurred the development of multifunctional
and smart bioadhesives with strong bioadhesion, antibacterial effect, real-time sensing …