Cell therapy trials for heart regeneration—lessons learned and future directions

P Menasché - Nature Reviews Cardiology, 2018 - nature.com
The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Regenerating the field of cardiovascular cell therapy

KR Chien, J Frisén, R Fritsche-Danielson… - Nature …, 2019 - nature.com
The retraction of> 30 falsified studies by Anversa et al. has had a disheartening impact on
the cardiac cell therapeutics field. The premise of heart muscle regeneration by the …

Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction

S Chen, W Fang, F Ye, YH Liu, J Qian, S Shan… - The American journal of …, 2004 - Elsevier
Sixty-nine patients who underwent primary percutaneous coronary intervention within 12
hours after onset of acute myocardial infarction were randomized to receive intracoronary …

[LIBRO][B] OZONE.

V Bocci - 2011 - Springer
Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

How to improve the survival of transplanted mesenchymal stem cell in ischemic heart?

L Li, X Chen, WE Wang, C Zeng - Stem Cells International, 2016 - Wiley Online Library
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

Endothelial and cardiac progenitor cells for cardiovascular repair: a controversial paradigm in cell therapy

V Bianconi, A Sahebkar, P Kovanen, F Bagaglia… - Pharmacology & …, 2018 - Elsevier
Stem cells have the potential to differentiate into cardiovascular cell lineages and to
stimulate tissue regeneration in a paracrine/autocrine manner; thus, they have been …

A randomized, open-label, multicenter trial for the safety and efficacy of adult mesenchymal stem cells after acute myocardial infarction

JW Lee, SH Lee, YJ Youn, MS Ahn… - Journal of Korean …, 2014 - synapse.koreamed.org
Recent studies suggest that the intracoronary administration of bone marrow (BM)-derived
mesenchymal stem cells (MSCs) may improve left ventricular function in patients with acute …

The acute and long‐term effects of intracoronary Stem cell Transplantation in 191 patients with chronic heARt failure: the STAR‐heart study

BE Strauer, M Yousef… - European journal of heart …, 2010 - Wiley Online Library
Aims Despite accumulated evidence that intracoronary bone marrow cell (BMC) therapy
may be beneficial in acute myocardial infarction, there are only limited data available on the …

Mesenchymal stem cells use integrin β1 not CXC chemokine receptor 4 for myocardial migration and engraftment

JE Ip, Y Wu, J Huang, L Zhang, RE Pratt… - Molecular biology of …, 2007 - Am Soc Cell Biol
Recent evidence has demonstrated the importance of bone marrow-derived mesenchymal
stem cells (BM-MSCs) in the repair of damaged myocardium. The molecular mechanisms of …

Cardiac cell therapy: where we've been, where we are, and where we should be headed

K Malliaras, E Marban - British medical bulletin, 2011 - academic.oup.com
Introduction Stem cell therapy has emerged as a promising strategy for the treatment of
ischemic cardiomyopathy. Sources of data Multiple candidate cell types have been used in …