Recent work has revealed that the neural activity patterns correlated with sensation,
cognition, and action often are not stable and instead undergo large scale changes over …

To perform computations with the efficiency necessary for animal survival, neocortical
microcircuits must be capable of reconfiguring in response to experience, while carefully …

INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …

Penetrating flexible electrode arrays can simultaneously record thousands of individual
neurons in the brains of live animals. However, it has been challenging to spatially map and …

Animals have exquisite control of their bodies, allowing them to perform a diverse range of
behaviours. How such control is implemented by the brain, however, remains unclear …

Perceptual constancy requires the brain to maintain a stable representation of sensory input.
In the olfactory system, activity in primary olfactory cortex (piriform cortex) is thought to …

The basal ganglia are known to influence action selection and modulation of movement
vigor, but whether and how they contribute to specifying the kinematics of learned motor …

Understanding the detailed dynamics of neuronal networks will require the simultaneous
measurement of spike trains from hundreds of neurons (or more). Currently, approaches to …

Electrophysiological methods are the gold standard in neuroscience because they reveal
the activity of individual neurons at high temporal resolution and in arbitrary brain locations …

The brain is a massive neuronal network, organized into anatomically distributed sub-
circuits, with functionally relevant activity occurring at timescales ranging from milliseconds …