Mini-puberty, physiological and disordered: Consequences, and potential for therapeutic replacement
J Rohayem, EC Alexander, S Heger… - Endocrine …, 2024 - academic.oup.com
There are 3 physiological waves of central hypothalamic-pituitary-gonadal (HPG) axis
activity over the lifetime. The first occurs during fetal life, the second—termed “mini-puberty” …
activity over the lifetime. The first occurs during fetal life, the second—termed “mini-puberty” …
Ontogeny of hypothalamus-pituitary gonadal axis and minipuberty: an ongoing debate?
C Bizzarri, M Cappa - Frontiers in Endocrinology, 2020 - frontiersin.org
The fetal hypothalamus-pituitary gonadal (HPG) axis begins to function during mid-gestation
but its activity decreases during late pregnancy due to the suppressive effects of placental …
but its activity decreases during late pregnancy due to the suppressive effects of placental …
Midpregnancy Phthalate and Phenol Biomarkers in Relation to Infant Body Composition: The Healthy Start Prospective Cohort
Background: Gestational phthalate and phenol exposure disrupts adipogenesis, contributing
to obesity in mice. Whether gestational phthalate or phenol exposure is associated with …
to obesity in mice. Whether gestational phthalate or phenol exposure is associated with …
The impact of chromosomal sex on cardiometabolic health and disease
CB Wiese, R Avetisyan, K Reue - Trends in Endocrinology & Metabolism, 2023 - cell.com
Many aspects of metabolism are sex-biased, from gene expression in metabolic tissues to
the prevalence and presentation of cardiometabolic diseases. The influence of hormones …
the prevalence and presentation of cardiometabolic diseases. The influence of hormones …
[HTML][HTML] Minipuberty of human infancy—A window of opportunity to evaluate hypogonadism and differences of sex development
CH Renault, L Aksglaede… - Ann Pediatr …, 2020 - synapse.koreamed.org
Activation of the hypothalamic-pituitary-gonadal (HPG) axis happens in 3 phases during life.
The first phase is during fetal life and is only separated from the second phase, called …
The first phase is during fetal life and is only separated from the second phase, called …
Impact of obesity in asthma: Possible future therapies
H Tashiro, Y Kurihara, Y Kuwahara… - Allergology …, 2024 - jstage.jst.go.jp
abstract Obesity is one of the factors associated with the severity of asthma. Obesity is
associated with aggravation of the pathophysiology of asthma, including exacerbations …
associated with aggravation of the pathophysiology of asthma, including exacerbations …
[HTML][HTML] Obesity, body composition, and sex hormones: implications for cardiovascular risk
Cardiovascular disease (CVD) continues to be the leading cause of death in adults,
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …
highlighting the need to develop novel strategies to mitigate cardiovascular risk. The …
[HTML][HTML] Body composition reference charts for infants from birth to 24 months: Multicenter Infant Body Composition Reference Study
Background Body composition assessment in the first 2 y of life provides important insights
into child nutrition and health. The application and interpretation of body composition data in …
into child nutrition and health. The application and interpretation of body composition data in …
Sex differences on adipose tissue remodeling: from molecular mechanisms to therapeutic interventions
Sexual dimorphism greatly influences adipose tissue remodeling, which is characterized by
changes in the activity, number, and/or size of adipocytes in response to distinct stimuli …
changes in the activity, number, and/or size of adipocytes in response to distinct stimuli …
Evidence on sex differences in sports performance
Sex differences in sports performances continue to attract considerable scientific and public
attention, driven in part by high profile cases of: 1) biological male (XY) athletes who seek to …
attention, driven in part by high profile cases of: 1) biological male (XY) athletes who seek to …