The immune microenvironment of malignant pleural mesothelioma: A literature review

AL Désage, G Karpathiou, M Peoc'h, ME Froudarakis - Cancers, 2021 - mdpi.com
Simple Summary Malignant pleural mesothelioma is a rare and aggressive tumour,
associated with asbestos exposure. Current therapeutic approaches for malignant …

Molecular pathology of lung cancer

JJ Saller, TA Boyle - Cold Spring Harbor …, 2022 - perspectivesinmedicine.cshlp.org
This overview of the molecular pathology of lung cancer includes a review of the most
salient molecular alterations of the genome, transcriptome, and the epigenome. The insights …

Efficacy and safety of pembrolizumab in patients with advanced mesothelioma in the open-label, single-arm, phase 2 KEYNOTE-158 study

TA Yap, K Nakagawa, N Fujimoto… - The lancet respiratory …, 2021 - thelancet.com
Background Malignant pleural mesothelioma (MPM) has few treatment options.
Pembrolizumab showed preliminary clinical benefit in programmed death ligand 1 (PD-L1) …

COL1A1 is a potential prognostic biomarker and correlated with immune infiltration in mesothelioma

C Zhang, S Liu, X Wang, H Liu… - BioMed Research …, 2021 - Wiley Online Library
Objective. Mesothelioma (MESO) is a rare tumor derived from mesothelium cells. The aim of
this study was to explore key candidate genes and potential molecular mechanisms for …

[HTML][HTML] Biomarkers in malignant pleural mesothelioma: current status and future directions

T Ahmadzada, G Reid, S Kao - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Ahmadzada et al. Biomarkers in mesothelioma who are candidates for surgery undergo
either extra-pleural pneumonectomy (EPP), which involves macroscopic removal of the …

High BIN1 expression has a favorable prognosis in malignant pleural mesothelioma and is associated with tumor infiltrating lymphocytes

T Ahmadzada, K Lee, C Clarke, WA Cooper, A Linton… - Lung Cancer, 2019 - Elsevier
Objectives A number of key immune regulators show prognostic value in malignant pleural
mesothelioma (MPM), but the association between Bridging integrator 1 (BIN1), indoleamine …

Expression of phosphorylated ribosomal protein S6 in mesothelioma patients-correlation with clinico-pathological characteristics and outcome: results from the …

JH Rüschoff, M Haberecker, Z Tsourti, K Nackaerts… - Modern …, 2022 - nature.com
Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Although
histology and pathologic stage are important prognostic factors, better prognostic …

Local therapies and modulation of tumor surrounding stroma in malignant pleural mesothelioma: a translational approach

D Lisini, S Lettieri, S Nava, G Accordino… - International Journal of …, 2021 - mdpi.com
Malignant Pleural Mesothelioma (MPM) is a rare and aggressive neoplasm of the pleural
mesothelium, mainly associated with asbestos exposure and still lacking effective therapies …

A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

BTV Duong, L Wu, BJ Green, F Bavaghar-Zaeimi… - …, 2020 - thelancet.com
Background Malignant pleural mesothelioma (MPM) is an aggressive cancer related to
asbestos exposure. Early diagnosis is challenging due to generic symptoms and a lack of …

[HTML][HTML] Expression of estrogen receptor beta (ERβ) and its prognostic value in pleural mesothelioma

JR Rodríguez-Cid, O García-Acevedo… - Journal of Thoracic …, 2019 - ncbi.nlm.nih.gov
Background Overexpression of estrogen receptors in malignant pleural mesothelioma has
shown an independent relation with a better prognosis of survival, and the use of selective …