Multiscale toughening mechanisms in biological materials and bioinspired designs

W Huang, D Restrepo, JY Jung, FY Su, Z Liu… - Advanced …, 2019 - Wiley Online Library
Biological materials found in Nature such as nacre and bone are well recognized as light‐
weight, strong, and tough structural materials. The remarkable toughness and damage …

Atypical femur fractures: review of epidemiology, relationship to bisphosphonates, prevention, and clinical management

DM Black, B Abrahamsen, ML Bouxsein… - Endocrine …, 2019 - academic.oup.com
Bisphosphonates (BPs) are highly effective in treating osteoporosis and reducing hip,
vertebral, and other fractures by as much as 50% to 70%. However, since 2006, atypical …

The renaissance of one-dimensional carbon nanotubes in tissue engineering

L Bao, X Cui, M Mortimer, X Wang, J Wu, C Chen - Nano Today, 2023 - Elsevier
The severe imbalance between supply and demand has remained a life-threatening
situation for patients undergoing organ resection or severe tissue damage. To resolve this …

Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance

AA Lloyd, B Gludovatz, C Riedel… - Proceedings of the …, 2017 - National Acad Sciences
Bisphosphonates are the most widely prescribed pharmacologic treatment for osteoporosis
and reduce fracture risk in postmenopausal women by up to 50%. However, in the past …

Radial bimetallic structures via wire arc directed energy deposition-based additive manufacturing

L Squires, E Roberts, A Bandyopadhyay - Nature Communications, 2023 - nature.com
Bimetallic wire arc additive manufacturing (AM) has traditionally been limited to depositions
characterized by single planar interfaces. This study demonstrates a more complex radial …

Increased mechanical loading through controlled swimming exercise induces bone formation and mineralization in adult zebrafish

S Suniaga, T Rolvien, A Vom Scheidt, IAK Fiedler… - Scientific Reports, 2018 - nature.com
Exercise promotes gain in bone mass through adaptive responses of the vertebrate
skeleton. This mechanism counteracts age-and disease-related skeletal degradation, but …

4D printed bio-inspired mesh composite materials with high stretchability and reconfigurability

C Zeng, L Liu, X **n, W Zhao, C Lin, Y Liu… - Composites Science and …, 2024 - Elsevier
Strain engineering such as Kirigami design offers viable solutions for transforming rigid or
even non-stretchable materials into highly stretchable structures, thus providing new …

An integrated experimental-computational framework to assess the influence of microstructure and material properties on fracture toughness in clinical specimens of …

A Demirtas, EA Taylor, B Gludovatz, RO Ritchie… - Journal of the …, 2023 - Elsevier
Microstructural and compositional changes that occur due to aging, pathological conditions,
or pharmacological treatments alter cortical bone fracture resistance. However, the relative …

Numerical analysis of low-speed impact response of sandwich panels with bio-inspired diagonal-enhanced square honeycomb core

QW Li, BH Sun - International Journal of Impact Engineering, 2023 - Elsevier
The diagonal-enhanced square grid configuration inspired by glass sponge has great
potential in mechanics, with geometries serving as honeycomb cores for sandwich panels …

Long-term effects of bisphosphonate therapy: perforations, microcracks and mechanical properties

S Ma, EL Goh, A **, R Bhattacharya, OR Boughton… - Scientific reports, 2017 - nature.com
Osteoporosis is characterised by trabecular bone loss resulting from increased osteoclast
activation and unbalanced coupling between resorption and formation, which induces a …