Epigenetics in cancer therapy and nanomedicine

A Roberti, AF Valdes, R Torrecillas, MF Fraga… - Clinical …, 2019 - Springer
The emergence of nanotechnology applied to medicine has revolutionized the treatment of
human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs …

Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy

J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …

DNA methylation in thyroid cancer

C Zafon, J Gil, B Pérez-González… - Endocrine-related …, 2019 - erc.bioscientifica.com
In recent years, cancer genomics has provided new insights into genetic alterations and
signaling pathways involved in thyroid cancer. However, the picture of the molecular …

Associations between artificial light at night and risk for thyroid cancer: a large US cohort study

D Zhang, RR Jones, P James, CM Kitahara, Q **ao - Cancer, 2021 - Wiley Online Library
Background Light at night (LAN) inhibits nighttime secretion of melatonin and may cause
circadian disruption, which may be a risk factor for cancer. Recent studies have linked high …

[HTML][HTML] ADAMTS proteases and cancer

S Cal, C López-Otín - Matrix biology, 2015 - Elsevier
ADAMTSs (A disintegrin and metalloprotease domains with thrombospondins motifs) are
complex extracellular proteases that have been related to both oncogenic and tumor …

An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression

AA Khan, X Liu, X Yan, M Tahir, S Ali… - Cancer and metastasis …, 2021 - Springer
Pancreatic cancer (PC) is assumed to be an intimidating and deadly malignancy due to
being the leading cause of cancer-led mortality, predominantly affecting males of older age …

[HTML][HTML] Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches

S Bhattacharya, RK Mahato, S Singh, GK Bhatti… - Life Sciences, 2023 - Elsevier
Thyroid cancer continues to exhibit a rising incidence globally, predominantly affecting
women. Despite stable mortality rates, the unique characteristics of thyroid carcinoma …

High Diagnostic Accuracy Based on CLDN10, HMGA2, and LAMB3 Transcripts in Papillary Thyroid Carcinoma

MC Barros-Filho, FA Marchi, CA Pinto… - The Journal of …, 2015 - academic.oup.com
Context: Thyroid nodules are common in adult population and papillary thyroid carcinoma
(PTC) is the most frequent malignant finding. The natural history of PTC remains poorly …

[HTML][HTML] Genomic and epigenomic profile of thyroid cancer

A Acuña-Ruiz, C Carrasco-López… - Best Practice & Research …, 2023 - Elsevier
Thyroid cancer is the most common malignancy of the endocrine system, and its incidence
has been steadily increasing. Advances in sequencing have allowed analysis of the entire …

Methylation in HOX Clusters and Its Applications in Cancer Therapy

A Paço, SA de Bessa Garcia, R Freitas - Cells, 2020 - mdpi.com
HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …