Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Smart polydopamine-based nanoplatforms for biomedical applications: state-of-art and further perspectives

H Xu, Y Zhang, H Zhang, Y Zhang, Q Xu, J Lu… - Coordination Chemistry …, 2023 - Elsevier
Thanks to rapid development of nanotechnology, studies have discovered an emerging
polymer nanomaterial—polydopamine (PDA) inspired by natural mussels. PDA possesses …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy

G He, Y Li, MR Younis, LH Fu, T He, S Lei, J Lin… - Nature …, 2022 - nature.com
Aminolevulinic acid-based photodynamic therapy heavily depends on the biological
transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an …

Highly penetrable and on-demand oxygen release with tumor activity composite nanosystem for photothermal/photodynamic synergetic therapy

Y Wang, S Luo, Y Wu, P Tang, J Liu, Z Liu, S Shen… - ACS …, 2020 - ACS Publications
A deep penetrating and pH-responsive composite nanosystem was strategically developed
to improve the efficacy of synergetic photothermal/photodynamic therapy (PTT/PDT) against …

Boosting H2O2‐Guided Chemodynamic Therapy of Cancer by Enhancing Reaction Kinetics through Versatile Biomimetic Fenton Nanocatalysts and the Second …

T Wang, H Zhang, H Liu, Q Yuan, F Ren… - Advanced Functional …, 2020 - Wiley Online Library
Fenton reaction–based chemodynamic therapy (CDT) has attracted considerable attention
for tumor treatment, because the Fenton reaction can degrade endogenous H2O2 within the …

Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

WL Liu, MZ Zou, T Liu, JY Zeng, X Li, WY Yu… - Nature …, 2019 - nature.com
Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using
exogenous antigens and adoptive cells, we show a concept of utilizing biologically …

Tumor Microenvironment‐Responsive Mesoporous MnO2‐Coated Upconversion Nanoplatform for Self‐Enhanced Tumor Theranostics

J Xu, W Han, P Yang, T Jia, S Dong, H Bi… - Advanced Functional …, 2018 - Wiley Online Library
The insufficient blood flow and oxygen supply in solid tumor cause hypoxia, which leads to
low sensitivity of tumorous cells and thus causing poor treatment outcome. Here …

A Porous Au@Rh Bimetallic Core–Shell Nanostructure as an H2O2‐Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and …

J Wang, J Sun, W Hu, Y Wang, T Chou… - Advanced …, 2020 - Wiley Online Library
In treatment of hypoxic tumors, oxygen‐dependent photodynamic therapy (PDT) is
considerably limited. Herein, a new bimetallic and biphasic Rh‐based core–shell …