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Unveiling the mechanisms and challenges of cancer drug resistance
Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …
treatment strategies are evolving due to innate and acquired resistance capacity, governed …
Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy
L Yang, A Li, Y Wang, Y Zhang - Signal Transduction and Targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …
human health. An altered microbiome can be associated with complex diseases …
Managing the TME to improve the efficacy of cancer therapy
MT Bilotta, A Antignani, DJ Fitzgerald - Frontiers in immunology, 2022 - frontiersin.org
The tumor microenvironment (TME) influences tumor growth, metastatic spread and
response to treatment. Often immunosuppression, mediated by the TME, impairs a beneficial …
response to treatment. Often immunosuppression, mediated by the TME, impairs a beneficial …
[HTML][HTML] Apoptosis deregulation and the development of cancer multi-drug resistance
Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …
respond well or respond poorly, to treatment and develop resistance to more than one anti …
[HTML][HTML] Targeting the tumor microenvironment: Potential strategy for cancer therapeutics
Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …
Unraveling the tumor microenvironment: Insights into cancer metastasis and therapeutic strategies
This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …
Role of hypoxia in the tumor microenvironment and targeted therapy
G Chen, K Wu, H Li, D **a, T He - Frontiers in oncology, 2022 - frontiersin.org
Tumor microenvironment (TME), which is characterized by hypoxia, widely exists in solid
tumors. As a current research hotspot in the TME, hypoxia is expected to become a key …
tumors. As a current research hotspot in the TME, hypoxia is expected to become a key …
Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer
Overcoming multidrug resistance (MDR) is one of the major challenges in cancer therapy. In
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …
[HTML][HTML] Innovative strategies for photodynamic therapy against hypoxic tumor
Photodynamic therapy (PDT) is applied as a robust therapeutic option for tumor, which
exhibits some advantages of unique selectivity and irreversible damage to tumor cells …
exhibits some advantages of unique selectivity and irreversible damage to tumor cells …
Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy
B Song, P Yang, S Zhang - Cancer communications, 2024 - Wiley Online Library
Cancer is a leading cause of death worldwide. Targeted therapies aimed at key oncogenic
driver mutations in combination with chemotherapy and radiotherapy as well as …
driver mutations in combination with chemotherapy and radiotherapy as well as …