Proteomic analysis reveals geographic variation in venom composition of Russell's Viper in the Indian subcontinent: Implications for clinical manifestations post …

B Kalita, SP Mackessy… - Expert review of proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: The Russell's Viper (RV)(Daboia russelii), a category I medically
important snake, is responsible for a significant level of morbidity and mortality in the Indian …

Quantitative proteomic analysis of venom from Southern India common krait (Bungarus caeruleus) and identification of poorly immunogenic toxins by immune …

A Patra, A Chanda, AK Mukherjee - Expert review of proteomics, 2019 - Taylor & Francis
Objectives: To study the venom proteome composition of Southern India (SI) Common Krait
(Bungarus caeruleus) and immunological cross-reactivity between venom against …

Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots

RR Senji Laxme, S Khochare, S Attarde… - PLoS neglected …, 2021 - journals.plos.org
Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …

Proteomic analysis to unravel the complex venom proteome of eastern India Naja naja: Correlation of venom composition with its biochemical and pharmacological …

S Dutta, A Chanda, B Kalita, T Islam, A Patra… - Journal of …, 2017 - Elsevier
The complex venom proteome of the eastern India (EI) spectacled cobra (Naja naja) was
analyzed using tandem mass spectrometry of cation-exchange venom fractions. About 75 …

Unraveling the proteome composition and immuno-profiling of western India Russell's viper venom for in-depth understanding of its pharmacological properties …

B Kalita, A Patra, AK Mukherjee - Journal of proteome research, 2017 - ACS Publications
The proteome composition of western India (WI) Russell's viper venom (RVV) was correlated
with pharmacological properties and pathological manifestations of RV envenomation …

A proteomic analysis of Pakistan Daboia russelii russelii venom and assessment of potency of Indian polyvalent and monovalent antivenom

AK Mukherjee, B Kalita, SP Mackessy - Journal of proteomics, 2016 - Elsevier
To address the dearth of knowledge on the biochemical composition of Pakistan Russell's
Viper (Daboia russelii russelii) venom (RVV), the venom proteome has been analyzed and …

Proteomic Analysis and Immuno-Profiling of Eastern India Russell's Viper (Daboia russelii) Venom: Correlation between RVV Composition and Clinical …

B Kalita, A Patra, A Das… - Journal of proteome …, 2018 - ACS Publications
The proteomes of Russell's viper venom (RVV) from Burdwan (RVV B) and Nadia (RVV N),
the two districts of West Bengal, eastern India (EI), were investigated by gel-filtration …

Quantitative proteomic analysis and antivenom study revealing that neurotoxic phospholipase A2 enzymes, the major toxin class of Russell's viper venom from …

B Kalita, S Singh, A Patra, AK Mukherjee - International journal of biological …, 2018 - Elsevier
The proteome composition of Russell's viper venom (RVV) from southern India (SI) was
investigated by 1D-SDS-PAGE of venom followed by tandem mass spectrometry analysis of …

The in vitro laboratory tests and mass spectrometry-assisted quality assessment of commercial polyvalent antivenom raised against the 'Big Four'venomous snakes of …

A Patra, D Banerjee, S Dasgupta, AK Mukherjee - Toxicon, 2021 - Elsevier
India has recorded the maximum snakebite deaths in the world. Intravenous administration
of polyvalent antivenom (PAV) raised against the 'Big Four'venomous snakes of India (Naja …

Anticoagulant mechanism and platelet deaggregation property of a non-cytotoxic, acidic phospholipase A2 purified from Indian cobra (Naja naja) venom: inhibition of …

S Dutta, D Gogoi, AK Mukherjee - Biochimie, 2015 - Elsevier
In the present study, anticoagulant and platelet modulating activities of an acidic
phospholipase A 2 (NnPLA 2-I) purified from Indian cobra Naja naja venom was …