Isolated growth hormone deficiency (GHD) in childhood and adolescence: recent advances

KS Alatzoglou, EA Webb, P Le Tissier… - Endocrine …, 2014 - academic.oup.com
The diagnosis of GH deficiency (GHD) in childhood is a multistep process involving clinical
history, examination with detailed auxology, biochemical testing, and pituitary imaging, with …

Development of the pituitary gland

KS Alatzoglou, LC Gregory… - Comprehensive …, 2020 - discovery.ucl.ac.uk
The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …

Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing

ASK Jones, DF Hannum, JH Machlin, A Tan, Q Ma… - Science …, 2024 - science.org
The reproductive and endocrine functions of the ovary involve spatially defined interactions
among specialized cell populations. Despite the ovary's importance in fertility and endocrine …

DLK1/PREF1 regulates nutrient metabolism and protects from steatosis

M Charalambous, ST Da Rocha, EJ Radford… - Proceedings of the …, 2014 - pnas.org
Nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance and obesity,
as well as progressive liver dysfunction. Recent animal studies have underscored the …

Altered expression of imprinted genes in Wilms tumors

J Hubertus, M Lacher, M Rottenkolber… - Oncology …, 2011 - spandidos-publications.com
Overexpression of insulin-like growth factor 2 (IGF2), an imprinted gene located on
chromosome 11p15, has been reported as a characteristic feature in various embryonal …

Single-cell transcriptomics identifies pituitary gland changes in diet-induced obesity in male mice

RE Ruggiero-Ruff, BH Le, PA Villa, NM Lainez… - …, 2024 - academic.oup.com
Obesity is a chronic disease with increasing prevalence worldwide. Obesity leads to an
increased risk of heart disease, stroke, and diabetes, as well as endocrine alterations …

Fluoride-related changes in the fetal cord blood proteome; a pilot study

ST Tuomivaara, SJ Fisher, SC Hall, DE Goin… - Environmental …, 2024 - Springer
Background Fluoride exposure during pregnancy has been associated with various effects
on offspring, including changes in behavior and IQ. To provide clues to possible …

DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons

C Villanueva, S Jacquier, N de Roux - PLoS One, 2012 - journals.plos.org
Delta-Like 1 Homolog, Dlk1, is a paternally imprinted gene encoding a transmembrane
protein involved in the differentiation of several cell types. After birth, Dlk1 expression …

[HTML][HTML] Discovery of transcriptional regulators and signaling pathways in the develo** pituitary gland by bioinformatic and genomic approaches

ML Brinkmeier, SW Davis, P Carninci, JW MacDonald… - Genomics, 2009 - Elsevier
We report a catalog of the mouse embryonic pituitary gland transcriptome consisting of five
cDNA libraries including wild type tissue from E12. 5 and E14. 5, Prop1df/df mutant at E14 …

[HTML][HTML] Integrative mRNA-miRNA interaction analysis associated with the immune response of Strongylocentrotus intermedius to Vibrio harveyi infection

P Hao, L Han, Z Quan, X **, Y Li, Y Wu… - Fish & Shellfish …, 2023 - Elsevier
Strongylocentrotus intermedius is one of the most economically valuable sea urchin species
in China and has experienced mass mortality owing to outbreaks of bacterial diseases such …