[HTML][HTML] 7-Ketocholesterol in disease and aging

A Anderson, A Campo, E Fulton, A Corwin… - Redox biology, 2020 - Elsevier
Ketocholesterol (7KC) is a toxic oxysterol that is associated with many diseases and
disabilities of aging, as well as several orphan diseases. 7KC is the most common product of …

Attenuation of 7-ketocholesterol-and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age …

T Nury, A Yammine, I Ghzaiel, K Sassi, A Zarrouk… - Ageing research …, 2021 - Elsevier
Age-related diseases for which there are no effective treatments include cardiovascular
diseases; neurodegenerative diseases such as Alzheimer's disease; eye disorders such as …

Impact of oxysterols on cell death, proliferation, and differentiation induction: current status

FA de Freitas, D Levy, A Zarrouk, G Lizard… - Cells, 2021 - mdpi.com
Oxysterols are oxidized derivatives of cholesterol produced by enzymatic activity or non-
enzymatic pathways (auto-oxidation). The oxidation processes lead to the synthesis of about …

Oxiapoptophagy: A type of cell death induced by some oxysterols

T Nury, A Zarrouk, A Yammine… - British Journal of …, 2021 - Wiley Online Library
Oxysterols are oxidized forms of cholesterol generated from cholesterol by auto‐oxidation,
enzymatic processes, or both. Some of them (7‐ketocholesterol, 7β‐hydroxycholesterol and …

Prevention by dietary polyphenols (resveratrol, quercetin, apigenin) against 7-ketocholesterol-induced oxiapoptophagy in neuronal N2a cells: Potential interest for the …

A Yammine, A Zarrouk, T Nury, A Vejux, N Latruffe… - Cells, 2020 - mdpi.com
The Mediterranean diet is associated with health benefits due to bioactive compounds such
as polyphenols. The biological activities of three polyphenols (quercetin (QCT), resveratrol …

Profile of fatty acids, tocopherols, phytosterols and polyphenols in mediterranean oils (argan oils, olive oils, milk thistle seed oils and nigella seed oil) and evaluation of …

A Zarrouk, L Martine, S Grégoire, T Nury… - Current …, 2019 - ingentaconnect.com
Background: The effects of vegetable oils on human health depend on their components.
Therefore, their profiles of lipid nutrients and polyphenols were determined. Objective: To …

Natural bioactive molecules as neuromedicines for the treatment/prevention of neurodegenerative diseases

A Babazadeh, FM Vahed, Q Liu, SA Siddiqui… - ACS …, 2023 - ACS Publications
The brain is vulnerable to different types of stresses, particularly oxidative stress as a result
of oxygen requirements/utilization in the body. Large amounts of unsaturated fatty acids …

Comparison of chemical composition and biological activities of Algerian seed oils of Pistacia lentiscus L., Opuntia ficus indica (L.) mill. and Argania spinosa L. Skeels

F Brahmi, S Haddad, K Bouamara… - Industrial Crops and …, 2020 - Elsevier
Many parameters can influence the chemical profiles and the biological activities of seed
oils. It was therefore of interest to study Algerian seed oils, whose caharacteristics are not …

Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol-and 7β-hydroxycholesterol …

L Rezig, I Ghzaiel, M Ksila, A Yammine, T Nury… - Steroids, 2022 - Elsevier
ketocholesterol and 7β-hydroxycholesterol are two oxysterols mainly formed by the
autoxidation of cholesterol. These two molecules are interconvertible via specific enzymes …

Dietary cholesterol oxidation products: Perspectives linking food processing and storage with health implications

Y Liu, X Yang, F **ao, F Jie, Q Zhang… - … Reviews in Food …, 2022 - Wiley Online Library
Dietary cholesterol oxidation products (COPs) are heterogeneous compounds formed
during the processing and storage of cholesterol‐rich foods, such as seafood, meat, eggs …