The haemoflagellate protozoan Trypanosoma cruzi (T. cruzi) is the causative agent of
Chagas disease (CD), a potentially life-threatening disease. Little by little, remarkable …

Owing to the urgent need for therapeutic interventions against the SARS-coronavirus 2
(SARS-CoV-2) pandemic, we employed an in silico approach to evaluate the SARS-CoV-2 …

Diverse structural frameworks are found in natural compounds and are well known for their
chemical and biological properties; such compounds include the imidazoles and oxazoles …

Imidazole derivatives display extensive applications in pharmaceutical chemistry and have
been investigated as bioactive compounds for medicinal chemistry. In this study, besides the …

Toxoplasmosis is a common parasitic disease caused by Toxoplasma gondii. Limitations of
available treatments motivate the search for better therapies for toxoplasmosis. In this study …

Toxoplasmosis, which affects more than a billion people worldwide, is a common parasitic
infection caused by the obligate intracellular parasite, Toxoplasma gondii. Current treatment …

Toxoplasma gondii is the etiological agent of toxoplasmosis, a common parasitic disease
that affects nearly one-third of the human population. The primary infection can be …

Background Therapeutic options for toxoplasmosis are limited. This fact underscores
ongoing research efforts to identify and develop better therapy. Previously, we reported the …

Background Our previous reports demonstrated the prospects of a new series of imidazoles
as a source of alternative anti-parasite treatments, thus warranting further studies that …

We have developed a convenient two-step, one-pot method for the facile synthesis of
cyanoimidazoles. By integrating a suite of reaction-monitoring techniques, we were able to …