Nociplastic pain is the semantic term suggested by the international community of pain
researchers to describe a third category of pain that is mechanistically distinct from …

The dorsolateral prefrontal cortex (DLPFC) is a functionally and structurally heterogeneous
region and a key node of several brain networks, implicated in cognitive, affective, and …

Sustained pain is a major characteristic of clinical pain disorders, but it is difficult to assess in
isolation from co-occurring cognitive and emotional features in patients. In this study, we …

Chronic pain is associated with reduced brain gray matter and impaired cognitive ability. In
this longitudinal study, we assessed whether neuroanatomical and functional abnormalities …

Objective Fibromyalgia (FM) is considered to be the prototypical central chronic pain
syndrome and is associated with widespread pain that fluctuates spontaneously. Multiple …

In this review, we integrate recent human and animal studies from the viewpoint of chronic
pain. First, we briefly review the impact of chronic pain on society and address current pitfalls …

A widely held belief within the clinical community is that chronic pain is associated with
cognitive impairment, despite the absence of a definitive systematic review or meta-analysis …

MR-based brain imaging technologies provide a suite of functional and structural metrics
that can be used to test hypotheses about the CNS mechanisms underlying pain perception …

The insula and cingulate cortices are implicated in emotional, homeostatic/allostatic,
sensorimotor, and cognitive functions. Non‐human primates have specific anatomical …

Chronic pain can be understood not only as an altered functional state, but also as a
consequence of neuronal plasticity. Here we use in vivo structural MRI to compare global …