Chitosan nanoparticles-based cancer drug delivery: application and challenges
Chitin is the second most abundant biopolymer consisting of N-acetylglucosamine units and
is primarily derived from the shells of marine crustaceans and the cell walls of organisms …
is primarily derived from the shells of marine crustaceans and the cell walls of organisms …
A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: statistical approach vs machine learning approach
Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the
most common cause of dementia in the elderly. As the number of elderly individuals …
most common cause of dementia in the elderly. As the number of elderly individuals …
Exploiting machine learning models to identify novel Alzheimer's disease biomarkers and potential targets
We still do not have an effective treatment for Alzheimer's disease (AD) despite it being the
most common cause of dementia and impaired cognitive function. Thus, research endeavors …
most common cause of dementia and impaired cognitive function. Thus, research endeavors …
A primer on the use of machine learning to distil knowledge from data in biological psychiatry
Applications of machine learning in the biomedical sciences are growing rapidly. This
growth has been spurred by diverse cross-institutional and interdisciplinary collaborations …
growth has been spurred by diverse cross-institutional and interdisciplinary collaborations …
The neurotoxin DSP-4 dysregulates the locus coeruleus-norepinephrine system and recapitulates molecular and behavioral aspects of prodromal neurodegenerative …
The noradrenergic locus coeruleus (LC) is among the earliest sites of tau and α-synuclein
pathology in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. The …
pathology in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. The …
MiRNA differences related to treatment-resistant schizophrenia
D Pérez-Rodríguez, MA Penedo… - International Journal of …, 2023 - mdpi.com
Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic
medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms …
medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms …
Integrative analysis of multi-omics and imaging data with incorporation of biological information via structural Bayesian factor analysis
Motivation With the rapid development of modern technologies, massive data are available
for the systematic study of Alzheimer's disease (AD). Though many existing AD studies …
for the systematic study of Alzheimer's disease (AD). Though many existing AD studies …
Potential plausible role of stem cell for treating depressive disorder: a retrospective review
Z Chang, Q Wang, L Li, B Jiang, X Zhou, H Zhu… - Molecular …, 2024 - Springer
Depression poses a significant threat to global physical and mental health, impacting
around 3.8% of the population with a rising incidence. Current treatment options primarily …
around 3.8% of the population with a rising incidence. Current treatment options primarily …
[HTML][HTML] Canopy FGF signaling regulator 3 affects prognosis, immune infiltration, and PI3K/AKT pathway in colon adenocarcinoma
XC Gao, BH Zhou, ZX Ji, Q Li… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Colon adenocarcinoma (COAD) is a malignant tumor of the digestive
system. The mechanisms underlying COAD development and progression are still largely …
system. The mechanisms underlying COAD development and progression are still largely …
A review and analysis of key biomarkers in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects over 50
million elderly individuals worldwide. Although the pathogenesis of AD is not fully …
million elderly individuals worldwide. Although the pathogenesis of AD is not fully …