The delivery of therapeutical molecules through the skin, particularly to its deeper layers, is
impaired due to the stratum corneum layer, which acts as a barrier to foreign substances …

The most popular methods for applying drugs transdermally are transdermal patches, topical
creams, and injectable hypodermic needles. Most therapeutic treatments are less effective …

The various kinds of nanocarriers (NCs) have been explored for the delivery of therapeutics
designed for the management of skin manifestations. The NCs are considered as one of the …

Microneedles (MNs) serve as a revolutionary paradigm in transdermal drug delivery,
heralding a viable resolution to the formidable barriers presented by the cutaneous …

This research aims to develop the formulation of Dissolving Microneedle Piperine (DMNs
PIP) and evaluate the effect of polymer concentration on characterisation and permeation …

Flavonoids are phytocompounds with varied chemical structures and are found in various
fruits, vegetables and medicinal plants. Flavonoids offer a wide range of health-promoting …

The high content of vitamin E, including tocopherols and tocotrienols (TCF-TTE), in palm oil
(Elaeis guineensis) has made it a promising candidate for the alternative treatment of atopic …

Microneedles invade skin tissue in a minimally invasive manner, with a small traumatic
surface and slight pain. There is growing interest in the potential application of microneedle …

Long-term pharmaceutical therapy is often essential for managing inflammatory and
proliferative ocular diseases. Traditional treatments, such as eye ointments or drops, face …

Phytochemicals, which are predominantly found in plants, hold substantial medicinal value.
Despite their potential, challenges such as poor oral bioavailability and instability in the …