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The chemistry and biological activities of peptides from amphibian skin secretions
X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …
environmental factors including microorganisms, parasites, predators, and physical factors …
Thinking on the construction of antimicrobial peptide databases: powerful tools for the molecular design and screening
K Zhang, D Teng, R Mao, N Yang, Y Hao… - International Journal of …, 2023 - mdpi.com
With the accelerating growth of antimicrobial resistance (AMR), there is an urgent need for
new antimicrobial agents with low or no AMR. Antimicrobial peptides (AMPs) have been …
new antimicrobial agents with low or no AMR. Antimicrobial peptides (AMPs) have been …
DADP: the database of anuran defense peptides
Anuran tissues, and especially skin, are a rich source of bioactive peptides and their
precursors. We here present a manually curated database of antimicrobial and other …
precursors. We here present a manually curated database of antimicrobial and other …
Structure and topology of the huntingtin 1–17 membrane anchor by a combined solution and solid-state NMR approach
M Michalek, ES Salnikov, B Bechinger - Biophysical journal, 2013 - cell.com
The very amino-terminal domain of the huntingtin protein is directly located upstream of the
protein's polyglutamine tract, plays a decisive role in several important properties of this …
protein's polyglutamine tract, plays a decisive role in several important properties of this …
PEGylation of the antimicrobial peptide LyeTx Ib maintains structure-related biological properties and improves selectivity
JC Moreira Brito, LR Carvalho… - Frontiers in Molecular …, 2022 - frontiersin.org
The biological activity of antimicrobial peptides and proteins is closely related to their
structural aspects and is sensitive to certain post-translational modifications such as …
structural aspects and is sensitive to certain post-translational modifications such as …
Designing a structure-function alphabet of helix based on reduced amino acid clusters
Several simple secondary structures could form complex and diverse functional proteins,
meaning that secondary structures may contain a lot of hidden information and are arranged …
meaning that secondary structures may contain a lot of hidden information and are arranged …
Rationalizing the membrane interactions of cationic amphipathic antimicrobial peptides by their molecular shape
B Bechinger - Current Opinion in Colloid & Interface Science, 2009 - Elsevier
Biophysical and structural studies of cationic amphipathic antimicrobial peptides have
revealed new mechanistic details concerning their membrane interactions. In interfacial …
revealed new mechanistic details concerning their membrane interactions. In interfacial …
ATP synthase: a molecular therapeutic drug target for antimicrobial and antitumor peptides
Z Ahmad, F Okafor, S Azim… - Current medicinal …, 2013 - ingentaconnect.com
In this review we discuss the role of ATP synthase as a molecular drug target for natural and
synthetic antimicrobial/antitumor peptides. We start with an introduction of the universal …
synthetic antimicrobial/antitumor peptides. We start with an introduction of the universal …
Mechanism of antibacterial action of dermaseptin B2: Interplay between helix− hinge− helix structure and membrane curvature strain
C Galanth, F Abbassi, O Lequin, J Ayala-Sanmartin… - Biochemistry, 2009 - ACS Publications
Dermaseptin B2 (Drs B2) is a 33-residue-long cationic, α-helical antimicrobial peptide
endowed with membrane-damaging activity against a broad spectrum of microorganisms …
endowed with membrane-damaging activity against a broad spectrum of microorganisms …
The structural and topological analysis of membrane-associated polypeptides by oriented solid-state NMR spectroscopy: established concepts and novel …
B Bechinger, JM Resende, C Aisenbrey - Biophysical chemistry, 2011 - Elsevier
Solid-state NMR spectroscopy is a powerful technique for the investigation of membrane-
associated peptides and proteins as well as their interactions with lipids, and a variety of …
associated peptides and proteins as well as their interactions with lipids, and a variety of …