Childhood cancer mutagenesis caused by transposase-derived PGBD5

M Yamada, RR Keller, RL Gutierrez, D Cameron… - Science …, 2024 - science.org
Genomic rearrangements are a hallmark of most childhood tumors, including
medulloblastoma, one of the most common brain tumors in children, but their causes remain …

Evolution of piggyBac Transposons in Apoidea

X Li, Z Guan, F Wang, Y Wang, E Asare, S Shi, Z Lin… - Insects, 2023 - mdpi.com
Simple Summary Bees are one of the mega-diverse class of insects in Hymenoptera. As
predators and the main crops pollinator, bees play an essential role in improving crop yield …

Knockdown of PGBD5 inhibits the malignant progression of glioma through upregulation of the PPAR pathway

P Luo, J Yang, L Jian, J Dong… - International …, 2024 - spandidos-publications.com
Glioma is the most common type of primary intracranial malignant tumor, and because of its
high invasiveness and recurrence, its prognosis remains poor. The present study …

Functional Characterization of the N-Terminal Disordered Region of the piggyBac Transposase

G Wachtl, É Schád, K Huszár, A Palazzo, Z Ivics… - International Journal of …, 2022 - mdpi.com
The piggyBac DNA transposon is an active element initially isolated from the cabbage
looper moth, but members of this superfamily are also present in most eukaryotic …

Analysis of DNA transposition by DNA transposases in human cells

Y Bigot, M Yamada, H Mueller, V Morell, S Alves… - bioRxiv, 2023 - biorxiv.org
This manuscript discusses the recent report “Cognate restriction of transposition by
piggyBac-like proteins” in Nucleic Acids Research by Beckermann et al and related recent …

A DNS transzpozonok funkcionális vizsgálata emlős sejtekben

P Lávay - 2024 - huveta.hu
A DNS transzpozonok olyan mobilis genetikai elemek, melyek kulcsszerepet játszanak
számos genomi folyamatban, ideértve a gazdagenomok evolúcióját is. A piggyBac …

[引言][C] „Nem-kódoló” és invazív elemek az eukarióta genomokban: szerepük és orvosbiológiai hasznosításuk

TI Orbán - 2024 - Természettudományi Kutatóközpont