Comprehensive plaque assessment by coronary CT angiography

P Maurovich-Horvat, M Ferencik, S Voros… - Nature Reviews …, 2014 - nature.com
Most acute coronary syndromes are caused by sudden luminal thrombosis due to
atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only …

PET imaging of inflammation in atherosclerosis

JM Tarkin, FR Joshi, JHF Rudd - Nature Reviews Cardiology, 2014 - nature.com
PET imaging of atherosclerosis can quantify several in vivo pathological processes
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …

[HTML][HTML] 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial

NV Joshi, AT Vesey, MC Williams, ASV Shah… - The Lancet, 2014 - thelancet.com
Background The use of non-invasive imaging to identify ruptured or high-risk coronary
atherosclerotic plaques would represent a major clinical advance for prevention and …

Histopathologic characteristics of atherosclerotic coronary disease and implications of the findings for the invasive and noninvasive detection of vulnerable plaques

J Narula, M Nakano, R Virmani, FD Kolodgie… - Journal of the American …, 2013 - jacc.org
Objectives: The goal of this study was to identify histomorphologic characteristics of
atherosclerotic plaques and to determine the amenability of some of these components to be …

Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose-positron emission tomography …

A Tawakol, ZA Fayad, R Mogg, A Alon… - Journal of the American …, 2013 - jacc.org
Objectives: The study sought to test whether high-dose statin treatment would result in
greater reductions in plaque inflammation than low-dose statins, using fluorodeoxyglucose …

Coronary arterial 18F-sodium fluoride uptake: a novel marker of plaque biology

MR Dweck, MWL Chow, NV Joshi, MC Williams… - Journal of the American …, 2012 - jacc.org
Objectives: With combined positron emission tomography and computed tomography (CT),
we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F …

Arterial inflammation in patients with HIV

S Subramanian, A Tawakol, TH Burdo, S Abbara, J Wei… - Jama, 2012 - jamanetwork.com
Context Cardiovascular disease is increased in patients with human immunodeficiency virus
(HIV), but the specific mechanisms are unknown. Objective To assess arterial wall …

Measurement of arterial activity on routine FDG PET/CT images improves prediction of risk of future CV events

AL Figueroa, A Abdelbaky, QA Truong, E Corsini… - JACC: Cardiovascular …, 2013 - jacc.org
Objectives: This study sought to determine whether arterial inflammation measured by 18F-
fluorodeoxyglucose positron emission tomography (18F-FDG-PET) improves prediction of …

Assessment of valvular calcification and inflammation by positron emission tomography in patients with aortic stenosis

MR Dweck, C Jones, NV Joshi, AM Fletcher… - Circulation, 2012 - Am Heart Assoc
Background—The pathophysiology of aortic stenosis is incompletely understood, and the
relative contributions of valvular calcification and inflammation to disease progression are …

Coronary adventitial and perivascular adipose tissue inflammation in patients with vasospastic angina

K Ohyama, Y Matsumoto, K Takanami, H Ota… - Journal of the American …, 2018 - jacc.org
Background: Recent studies suggested that perivascular components, such as perivascular
adipose tissue (PVAT) and adventitial vasa vasorum (VV), play an important role as a source …